Hormonske spremembe in vstop v pomenopavzo
Hormonal changes and entering postmenopause

slovenian

2025

volume 76, issue 2

hormonal changes   menopausal transition   postmenopause

Slovensko farmacevtsko društvo
(Obvezni izvod spletne publikacije)

Menarche and menopause are key physiological milestones in a woman’s life, triggering many physical and mental changes. In 2011, the World Health Organization updated the nomenclature of reproductive aging, dividing it into different stages and introducing the concept of the menopausal transition. Menopausal transition usually occurs around the age of 40 and brings many hormonal changes and an impact on menstrual cycles. The formation of anti-Müllerian hormone and estradiol decreases, followed by an increase in follicle-stimulating hormone. A decrease in the quality of egg follicles leads to reduced fertility and the absence of ovulation, and periods become irregular and prolonged. The progression to early postmenopause is defined by the last menstrual period. The period is accompanied by problems with thermoregulation, urogenital changes, a higher risk of cardiovascular diseases and changes in psychological health. In late postmenopause, hormone levels stabilize, but they have a lasting impact on a woman’s overall health.

20.05.2026