Botulizem
Botulism

slovenian

2004

volume 73, issue 12

Botulism   Clostridium Botulinum   Diagnosis   Epidemiology   Therapy   toxin

Slovensko zdravniško društvo
(Obvezni izvod spletne publikacije)

Background. Human botulism is a serious, relatively rare and potencial lethal disease, caused by Clostridium botulinum, a gram positive obligat anaerobic spore forming bacili which strain produced seven potent nevrotoksins (type A-G). It can be found in soil and marine sediment troughout the world and alsocolonizes the gastrointestinal tract of fishes, birds and mammals. Human botulism is usually caused by neurotoxin type A, B, E and rerely F. Type C, D and E cause illness in mammals, birds and fish. Botulism is not transmitted byhuman to human contact. More types of botulism are recognised: foodborne botulism, infant botulism, wound botulism, adult infection botulism, inadvertent botulism. Botulism is characterised by simmetrical, descendenting paralisys of motor and autonomic nerves usually beginning with cranial nerves.The pacient alert, afebril and without sensory disturbance. Botulinum toxin is an agent of biological warfare. Conclusions. From 1985 to 2003 are identified 44 cases of foodborn botulism in Slovenia. We described the outbreak of foodborn botulism in family epidemic, which source is domestic rawsmoke ham.

10.04.2014