Vpliv okolja na razvoj avtoimunskih bolezni

english
slovenian

2022

autoimmune diseases   diet   environment   infections   stress   toxins

Narodna in univerzitetna knjižnica
(Obvezni izvod spletne publikacije)

Autoimmune diseases are chronic diseases whose management, despite advances in treatment and diagnosis, remains unsatisfactory and are associated with significant disability and premature mortality, with significant personal, social and economic consequences. The number of patients, suffering from autoimmune diseases has been steadily increasing year by year and they represent an increasing burden on public healthcare. Thus, more resources are being funnelled into the field. From currently existing data the main factors that impact the immune tolerance negatively are internal ones (the genetic predisposition, the immune system’s shortcomings, hormones (gender, stress)), and external ones (Infections, smoking, medications, nutrition, environmental toxins, intestinal microbiota). People of the modern world are more than ever heavily exposed to detrimental environmental factors, mostly due to excessive pollution. The purpose of the article is to present individual environmental factors, what we know about their effect on the development of autoimmune diseases and the mechanisms responsible for autoimmunity. It is crucial to discover environmental factors, that trigger specific autoimmune diseases, which would allow for the development of precautionary programs to commence and could preserve the health of millions of people. The objective of this article is to encourage further research in the field.

04.09.2024