Ekonomsko breme nalezljivih bolezni – metoda meritve količine antibiotikov pri hospitaliziranih bolnikih
Economic burden of infectious diseases –quantity metrics method to measure antibiotic use in inpatients

slovenian

2023

volume 92, issue 7/8

admissions   antibiotic consumption   cost   defined daily dose   hospital care days

Slovensko zdravniško društvo
(Obvezni izvod spletne publikacije)

Irregular and uncontrolled consumption of antibiotics in hospitals and outside the hospital environment, promotes the development of resistant mutants, high costs, and side effects. In recent years, multi-disciplinary cooperation has been recommended; the international DRIVE-AB Project results have reviewed the list of 20 indicators for measuring the amount of antibiotics in hospitalized patients (IQMs). Our research was aimed to estimate the amount of antibiotics consumed according to IQM indicators. In the retrospective study, from 2014 to 2018 in selected Slovenian hospitals, the use of antibiotics with the IQMs method was calculated. We calculated DDO/100 bed-days (IQM1), DDO/100 admissions (IQM2), DDO/(100 BOD/CMI) (IQM3), and the correlation between DDO/100 BOD and CMI and DDD/100 admissions and CMI (IQM 12) and the cost of hospitalization calculated in EUR (IQM12). The IBMI SPSS package (Statistics for Windows, Version 21.0) was used for statistical analysis. We used descriptive statistics and the Pearson correlation method and the Linerne regression to analyze the data. For the significance, we considered p < 0.05. In 2014, the consumption of antibiotics in all the hospitals involved was, on average, calculated by IQM 1 55,66, IQM 2 288, and IQM 3 21.66. We proved a strong correlation between DDO/100 admissions and CMI (P = 0.01) DDO/100 bed-days and CMI (p < 0.001) (IQM 12). The cost of hospitalization for infectious diseases has risen since 2014 from around 162 million to 192 million in 2018 (IQM12). This information is important for monitoring the situation and forecasting the trends in health care and consumption of resources in Slovenia. They are important for policies and experts in this field (infectious diseases specialists) because they can anticipate the use of funds based on calculated costs and affect cost reductions.

05.04.2024