369 KB32 KB192920262023Pokrajac, Tatjanaštevilka:7/8letnik:92str. 293-301DOI:10.6016/ZdravVestn.3154ISSN:1318-0347COBISSID:163546115URN:URN:NBN:SI:doc-G30JEHK3slSlovensko zdravniško društvoZdravniški vestnikadmissionsantibiotic consumptionbolnišnični oskrbni dnevicostdefined daily dosedefinirani dnevni odmerekhospital care daysporaba antibiotikovsprejemistrošekEkonomsko breme nalezljivih bolezni – metoda meritve količine antibiotikov pri hospitaliziranih bolnikih| Economic burden of infectious diseases –quantity metrics method to measure antibiotic use in inpatients|Irregular and uncontrolled consumption of antibiotics in hospitals and outside the hospital environment, promotes the development of resistant mutants, high costs, and side effects. In recent years, multi-disciplinary cooperation has been recommended; the international DRIVE-AB Project results have reviewed the list of 20 indicators for measuring the amount of antibiotics in hospitalized patients (IQMs). Our research was aimed to estimate the amount of antibiotics consumed according to IQM indicators. In the retrospective study, from 2014 to 2018 in selected Slovenian hospitals, the use of antibiotics with the IQMs method was calculated. We calculated DDO/100 bed-days (IQM1), DDO/100 admissions (IQM2), DDO/(100 BOD/CMI) (IQM3), and the correlation between DDO/100 BOD and CMI and DDD/100 admissions and CMI (IQM 12) and the cost of hospitalization calculated in EUR (IQM12). The IBMI SPSS package (Statistics for Windows, Version 21.0) was used for statistical analysis. We used descriptive statistics and the Pearson correlation method and the Linerne regression to analyze the data. For the significance, we considered p < 0.05. In 2014, the consumption of antibiotics in all the hospitals involved was, on average, calculated by IQM 1 55,66, IQM 2 288, and IQM 3 21.66. We proved a strong correlation between DDO/100 admissions and CMI (P = 0.01) DDO/100 bed-days and CMI (p < 0.001) (IQM 12). The cost of hospitalization for infectious diseases has risen since 2014 from around 162 million to 192 million in 2018 (IQM12). This information is important for monitoring the situation and forecasting the trends in health care and consumption of resources in Slovenia. They are important for policies and experts in this field (infectious diseases specialists) because they can anticipate the use of funds based on calculated costs and affect cost reductionsNepravilna in nenadzorovana poraba antibiotikov v bolnišnicah, pa tudi v zunajbolnišničnem okolju, spodbuja razvoj od-pornih različic povzročiteljev, visoke stroške in neželene učinke. V zadnjih letih priporočajo večdisciplinarno sodelovanje, in sicer spremljanje rezultatov mednarodnega projekta DRIVE- AB. Pregledali smo seznam 20 kazalcev za meritve količine antibiotikov pri hospitaliziranih bolnikih (angl. identify quantity metrics, IQM). Namen naše raziskave je bil oceniti količino porabljenih antibiotikov po kazalcih IQM. V retrospektivni študiji smo v obdobju od 2014–2018 v 2 univerzitetnih in 10 splo-šnih bolnišnicah v Sloveniji izračunali porabo antibiotikov z metodo IQM. Izračunali smo definirani dnevni odmerek (DDO) na 100 bolnišničnih oskrbnih dni (BOD) (IQM 1), DDO/100 sprejemov (IQM 2), DDO/100 BOD/ (angl. case mix index, CMI) (IQM 3) in korelacijo med DDO/100 BOD in CMI in DDO/100 sprejemov in CMI (IQM 12) ter strošek hospitalizacije, izračunan v EUR (IQM 12). Za statistično analizo smo uporabili paket IBMI SPSS. Za analizo podatkov smo uporabili opisno statistiko in metodo Pearsonove korelacije in linearne regresije. Za statistično značilnost smo upoštevali p < 0,05. Od leta 2014 do leta 2018 je bila povprečna poraba antibiotikov v vseh vključenih bolnišnicah 55,10 DDO/100 BOD, 286 DDO/100 spreje-mov. IQM 3 pa je bila 26,78. Dokazali smo močno korelacijo med DDO/100 sprejemov in CMI (p = 0,01) in DDO/100 BOD in CMI (p < 0,001) (IQM 12). Strošek hospitalizacije za nalezljive bolezni se je povečal od leta 2014 do leta 2018 od okrog 162 miljonov do 192 miljonov (IQM12). Tovrstni podatki so pomembni za napovedovanje porabe antibiotikov v slovenskih bol-nišnicah in spremljanje stanja in napovedovanje gibanj na področju zdravstvenega varstva in porabe sredstev v Sloveniji. Pomembni so za politiko in tudi strokovnjake na tem področju (infektologe), ker lahko na podlagi izračunanih stroškov predvidijo porabo sredstev in vplivajo na zmanjšanje stroškovTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo