The limits of ‘Generally Recognized As Safe’ classification for inhaled compounds in Electronic Nicotine Delivery Systems

Contibutor(s)

Vinko, Luka (author)
Devetak, Iztok (author)
Saksida, Tine (author)
Kocmut, Tjaša (author)
Trebše, Polonca (author)
Bavcon Kralj, Mojca (author)

Language

english

Source

Acta chimica slovenica

Year

2026

Numbering

volume 73, issue 2

Publisher

Slovensko kemijsko društvo

Provider

Slovensko kemijsko društvo
(Obvezni izvod spletne publikacije)

description

Electronic Nicotine Delivery Systems (ENDS) liquids contain compounds deemed safe for ingestion “Generally Recognized As Safe” (GRAS), yet lack inhalation safety data, posing risks, especially to adolescents. This study analysed chemical discrepancies in ENDS via gas chromatography–mass spectrometry and surveyed Slovenian secondary students on nicotine use. Analysis revealed cytotoxic substances when inhaled and unlisted solvents, exposing a mismatch between labelled and actual content. Most adolescents who used ENDS focused only on nicotine percentage and largely ignored product composition, despite knowing nicotine is harmful. Findings stress the need for toxicological evaluation, clearer labelling, stricter regulation, and targeted youth education.

Rights

URN

URN:NBN:SI:DOC-9ETJ4Q3S

COBISSID

283174147

DOI

10.17344/acsi.2025.9528

Added

07.10.2026

Metadata

Citation

APA:

Vinko, Luka, Devetak, Iztok, Saksida, Tine, Kocmut, Tjaša, Trebše, Polonca, Bavcon Kralj, Mojca (2026). The limits of ‘Generally Recognized As Safe’ classification for inhaled compounds in Electronic Nicotine Delivery Systems. Acta chimica slovenica, volume 73, issue 2, str. 343-351. URN:NBN:SI:DOC-9ETJ4Q3S from http://www.dlib.si

MLA:

Vinko, Luka, Devetak, Iztok, Saksida, Tine, Kocmut, Tjaša, Trebše, Polonca, Bavcon Kralj, Mojca. "The limits of ‘Generally Recognized As Safe’ classification for inhaled compounds in Electronic Nicotine Delivery Systems." Acta chimica slovenica volume 73. issue 2 (2026) str. 343-351.
<http://www.dlib.si/?URN=URN:NBN:SI:DOC-9ETJ4Q3S>

Acta chimica slovenica
1993-
(Assembly record)