Current guidelines for venom immunotherapy suggest that immunotherapy should be performed only in patients with IgE mediated systemic reactions. However, opinions on the diagnosis and treatment of patients with systemic reactions inthe absence of IgE are quite varied. We present a patient with a history of atypical systemic reactions after a bee sting. Skin tests and specific IgE forbee venom were negative. We performed a sting provocation test in order to characterize the nature and mechanism of reaction. The provocation test was positive and mast cell activation was proved by tryptase elevation. We decidedto treat the patient with immunotherapy. After beginning immunotherapy we were able to detect specific IgE for bee venom in the serum.

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URN

URN:NBN:SI:DOC-WYVFCUFM

COBISSID

22699225

Added

11.04.2014

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Citation

APA:

Zidarn, Mihaela, Košnik, Mitja, Drinovec, Igor (2007). Anaphylaxis after Hymenoptera sting without detectable specific IgE. Acta dermatovenerologica Alpina, Pannonica et Adriatica, volume 16, issue 1, str. 31-33. URN:NBN:SI:DOC-WYVFCUFM from http://www.dlib.si

MLA:

Zidarn, Mihaela, Košnik, Mitja, Drinovec, Igor. "Anaphylaxis after Hymenoptera sting without detectable specific IgE." Acta dermatovenerologica Alpina, Pannonica et Adriatica volume 16. issue 1 (2007) str. 31-33.
<http://www.dlib.si/?URN=URN:NBN:SI:DOC-WYVFCUFM>

Acta dermatovenerologica Alpina, Pannonica et Adriatica
1992-
(Assembly record)