Darier disease is a rare autosomal dominant genodermatosis that initially first presents in adolescence with scaly reddish brown keratotic papules and plaques with a seborrheic and intertriginous distribution. The absence of specific targeted medications complicates the treatment process, and managing resistant cases can prove challenging due to recurrent exacerbations that may result in serious complications such as secondary bacterial and viral infections. Treatments of choice include antiseptics, topical corticosteroids, and systemic retinoids, mainly acitretin and isotretinoin. We report the case of a female patient with Darier disease that was unsuccessfully treated with acitretin and isotretinoin but showed significant improvement with alitretinoin. Previous reports on the efficacy of alitretinoin in Darier disease are reviewed.

Rights

URN

URN:NBN:SI:DOC-TM0WWAGJ

COBISSID

180826883

DOI

10.15570/actaapa.2023.34

Added

16.07.2024

Metadata

Citation

APA:

Pagon, Andreja, Dolenc-Voljč, Mateja (2023). Efficacy of alitretinoin in the treatment of Darier disease. Acta dermatovenerologica Alpina, Pannonica et Adriatica, volume 32, iss. 4, str. 191-195. URN:NBN:SI:DOC-TM0WWAGJ from http://www.dlib.si

MLA:

Pagon, Andreja, Dolenc-Voljč, Mateja. "Efficacy of alitretinoin in the treatment of Darier disease." Acta dermatovenerologica Alpina, Pannonica et Adriatica volume 32. iss. 4 (2023) str. 191-195.
<http://www.dlib.si/?URN=URN:NBN:SI:DOC-TM0WWAGJ>

Acta dermatovenerologica Alpina, Pannonica et Adriatica
1992-
(Assembly record)