Biološka zdravila za zdravljenje hormonalnih aken : različni pristopi zdravljenja dermatoveneroloških bolezni

slovenian

2025

acne   biological drugs   biological molecule inhibitors   genetic engineering   multifactorial pathophysiology   stem cell therapy

Narodna in univerzitetna knjižnica
(Obvezni izvod spletne publikacije)

Acne is, especially among adolescents and young adults, a widespread dermatological condition with a multifactorial pathogenesis. The desire for more effective therapeutic outcomes with fewer side effects is driving improvements in existing treatment approaches, as well as the development of entirely new ones. The development of modern biological and biotechnological therapies is based on a thorough understanding of disease pathogenesis, which enables action on specific therapeutic targets. Antibodies that inhibit certain acne-related factors such as certain cytokines and enzymes are commonly used, but most of these biological drugs are off-label, meaning they are not registered for this indication. The potential of using genetic engineering for the purpose of delivering the active substance to the site of inflammation and stem cells to limit the inflammatory response is also being explored.

09.12.2025