Zasevni jetrni gastrinom
Gastrinoma of the liver

slovenian

1997

volume 36, issue 1

Društvo Medicinski razgledi
(Obvezni izvod spletne publikacije)

The gastrinoma was first described by the surgeons Zollinger and Ellison in 1955. The basic characteristics of this disese include an endocrine gastrin-secreting tumor of the gastrointestinal tract, gastric hypersecretion and recurrent gastric, duodenal and jejunal ulcers. The author reports on a 49-year-old female patient in whom a duodenal ulcer and two liver tumors, 10 and 6 cm in diameter, involving the right and the left lobe, respectively, were diagnosed in 1983. A liver biopsy specimen, obtained during explorative laparotomy, was defined histological as a metastatic small-cell epithelial tumor with an organoid endocrine pattern. Its morphological pattern was that of a tumor of series. A gatrinoma was verified by immunohistochemical staining. Serum gastrin levels exceeded the normal range by 10 times. The patient refused any further treatment. In the following years, she received several conservative treatments for sequelae of ther ulcer disease. For the past three years she has been treated on an out-patient basis, mostly for chronic diarrhea.

02.07.2015