Development of biomimetic sensors to determine the functionality of in vitro cell models
Razvoj biomimetičnih senzorjev za določanje funkcionalnosti in vitro celičnih modelov

Contibutor(s)

Frangež, Matjaž (author)
Glisik, Noah Emil (author)
Kaiser, Maša (author)
Vezjak, Jaro (author)
Žnidaršič, Matic (author)
Zidarič, Tanja (author)
Maver, Tina (author)

Language

english

Source

Anali PAZU

Year

2024

Numbering

volume 14, issue 2

Content

biomimetic sensors insulin MIP sensor molecular imprinting polypyrrole matrix

Publisher

Univerzitetna založba Univerze v Mariboru

Provider

Združenje Pomurska akademsko znanstvena unija
(Obvezni izvod spletne publikacije)

description

Advances in biomedical science have enabled the development of in vitro models that mimic human tissues. Non-invasive real-time monitoring of these models would provide valuable insights without disrupting the cellular environment. This study explores the use of molecularly imprinted polymers (MIPs) for this purpose, focusing on insulin and lactate as biomarkers of cellular metabolism. MIP sensors were created by electropolymerizing pyrrole around insulin or lactate templates on carbon electrodes. The sensors showed high sensitivity and selectivity, with detection ranges of 20.0–70.0 pM for insulin (LOD: 2.41 pM) and 0.5–3.0 mM for lactate. These findings highlight MIPs’ potential for personalized diagnostics and therapy monitoring.

Rights

URN

URN:NBN:SI:DOC-B7KPW9S5

COBISSID

223684355

DOI

10.18690/analipazu.14.2.39-57.2024

Added

10.02.2025

Metadata

Citation

APA:

Frangež, Matjaž, Glisik, Noah Emil, Kaiser, Maša, Vezjak, Jaro, Žnidaršič, Matic, Zidarič, Tanja, Maver, Tina (2024). Development of biomimetic sensors to determine the functionality of in vitro cell models. Anali PAZU, volume 14, issue 2, str. 39-57. URN:NBN:SI:DOC-B7KPW9S5 from http://www.dlib.si

MLA:

Frangež, Matjaž, Glisik, Noah Emil, Kaiser, Maša, Vezjak, Jaro, Žnidaršič, Matic, Zidarič, Tanja, Maver, Tina. "Development of biomimetic sensors to determine the functionality of in vitro cell models." Anali PAZU volume 14. issue 2 (2024) str. 39-57.
<http://www.dlib.si/?URN=URN:NBN:SI:DOC-B7KPW9S5>

Anali PAZU
2011-
(Assembly record)

Development of biomimetic sensors to determine the functionality of in vitro cell modelsRazvoj biomimetičnih senzorjev za določanje funkcionalnosti in vitro celičnih modelov

Development of biomimetic sensors to determine the functionality of in vitro cell models
Razvoj biomimetičnih senzorjev za določanje funkcionalnosti in vitro celičnih modelov