Cortico-basal ganglionic degeneration : radiological and functional features : radiološke in funkcionalne značilnosti

english

2002

volume 36, issue 4

Apraxia   Basal Ganglia Diseases   Diagnosis   Fluorine Radioisotopes   Magnetic Resonance Angiography   Magnetic Resonance Imaging   Nerve Degeneration

Društvo radiologije in onkologije
(Obvezni izvod spletne publikacije)

Background. Cortico-basal ganglionic degeneration is a rare degenerative pathology that involves parietal areas and gradually determines frontal involvement. The aim of our work was to describe the main radio- logical findings in this pathology and to evaluate the cortical activation in these patients by f-MRI during simple and complex movements. Patients and methods. We have evaluated eight patients with morphological and functional magnetic res- onance by using a 1.5 T imager. Results. Morphological evaluation: We found an asymmetric perirolandic cortical atrophy in seven pa- tients, a mild hyperintensity in the perirolandic cortex in five patients, a mild atrophy of the basal ganglia in seven patients and, in one, a hypointensity in the lenticular nuclei. In one patient the morphological as- pect was normal. Functional evaluation: The most important aspect was the hypoactivation of theparietal areas during the movement with the affected hand in all the patients. Conclusions. We consider f-MRI a helpful tool for the diagnosis and follow-up of this pathology.

16.09.2009