Kirurško zdravljenje malignega melanoma
Surgical treatment of malignant melanoma

slovenian

1999

volume 33, suppl. 1

Onkološki inštitut Ljubljana

Although the incidence and the mortality rates of malignant melanoma (MM) havebeen increasing worldwide and in Slovenija for the last several decades, the survival rates are improving. The apparent contradiction may be expained by the increase in early diagnnosis of MM. If detected early in its clinical course MM can be cured by a simple surgical excision in majority of patients. The decision about the margins of the surgical excision of the primary melanoma site has been made more rational through correlations of rates of local control with different margins of resection in relation to the domianantprognostic factor for localized melanoma, the thickness of the lesion. When possible, primary closure of the post-excisional defect should beperformed. If primary closure is impossible, the wound may be closed by split or full thickness skin grafting, local, regional or free flaps. Electivedissection has not been shown in prospective randomized trials to alter survival significantly. Surgical treatment of distant metastases is indicated only as palliation of a solitary symptomatic lesion (brain metastases, lung or gastrointestinal metastases).

12.12.2023