Antifungal treatment is becoming more and more important as the incidence of invasive fungal infections is increasing. Currently, several antimycotics withdiverse mechanisms of action are available, but their usage is often limited by their adverse effects and resistance. Novel strategies for the treatment of fungal infections are as follows: high-dose therapy, modulation of the pharmacokinetic properties of the drugs, combination therapy, immune system enhancement, and the development of new antifungal agents. Ideal antimycotics would have selectivity to fungal cells, low rates of resistance, broad antifungal activity, reduced toxicity and improved efficacy. The most promising antifungals are those targeting fungal cell wall components, proteinbiosynthesis and signaling pathways.

Rights

URN

URN:NBN:SI:DOC-V753QGBB

COBISSID

26425305

Added

26.05.2014

Metadata

Citation

APA:

Brunskole Švegelj, Mojca, Lanišnik-Rižner, Tea, Stojan, Jure (2009). Antimikotiki. Farmacevtski vestnik, volume 60, issue 6, str. 295-302. URN:NBN:SI:DOC-V753QGBB from http://www.dlib.si

MLA:

Brunskole Švegelj, Mojca, Lanišnik-Rižner, Tea, Stojan, Jure. "Antimikotiki." Farmacevtski vestnik volume 60. issue 6 (2009) str. 295-302.
<http://www.dlib.si/?URN=URN:NBN:SI:DOC-V753QGBB>

Farmacevtski vestnik
1950-
(Assembly record)

številka

Farmacevtski vestnik
2009
(Complete issue)

Antimikotiki : sedanje in nove možnosti zdravljenja glivičnih okužbAntimycotics : current and novel strategies for treatment of fungal infections

Antimikotiki : sedanje in nove možnosti zdravljenja glivičnih okužb
Antimycotics : current and novel strategies for treatment of fungal infections