Presejalno določanje holesterola pri pet let starih otrocih v Sloveniji
Screening for hypercholesterolemia in 5 year old children in Slovenia

slovenian

2003

volume 72, issue 1

Blood   Body Mass Index   cardiovascular disease   child   Child, Preschool   Cholesterol   Mass Screening   Sex Factors

Slovensko zdravniško društvo
(Obvezni izvod spletne publikacije)

Background. Cardiovascular diseases represent the most frequent cause of morbidity and mortality in developed countries. Blood cholesterol concentration inffluences the progression of atherosclerosis and most developed countries started programs for early detection of hypercholesterolemia. The study presents data analysis related to the total cholesterol concentrations obtained from 5-year old children. Additionally, guidelines for improving the follow-up work with children having hypercholesterolemia are presented. Methods. Values of total cholesterol concentration of 2742 children born 1995 or 1996 were obtained from 17 pediatric primary care facilities in Slovenia. Data analysis included values of body mass index (BMI). The study was approved by the State Committee for Medical Ethics (103/02/02). Results. Values of total cholesterol concentrationwere not distributed according to the normal distribution. Total cholesterol concentration was significantly higher in girls (median 4.41 mmol/L, 5th percentile 3.3 mmol/l and 95th percentile 5.8 mmol/L) compared to boys (median 4.3 mmol/L, 5th percentile 3.2 mmol/l and 95th percentile 5.6 mmol/L) (p < 0.0001). Twenty-one percent of values were above 5 mmol/L, 15% above 5.2 mmol/L and 2.8% above 6 mmol/L. Total cholesterol concentration did not correlate with the BMl. (Abstract truncated at 2000 characters).

10.04.2014