Renal vascular resistance in patients with chronic renal failure
Renalna vaskularna rezistenca pri bolnikih s kronično ledvično odpovedjo

english

2000

volume 34, issue 4

Onkološki inštitut Ljubljana

Duplex Doppler sonography has the potential to provide physiological information concerning renal arterial blood flow and resistance. The purpose of the study is to evaluate duplex Doppler sonography for assessing renal vascular resistance (RVR) in patients with chronic renal failure. Materials and methods. Resistive indices (RIs) and pulsatility indices (PIs) were measured in the intrarenal arteries of 30 patients with chronic renal failure and 20 control subjects. RIs and PIs of control subjects were compared to those of the patients with chronic renal failure and correlated with the laboratory and clinical findings. Results. In the control subjects, the mean RI was 0.59+-0.03 (+-SD) and mean PI was 1.00+-0.11. In the patients with chronic renal failure, the mean RI was 0.71+-0.11 and mean PI was 1.69+-0.21. Elevated RIs and PIs were associated with the progression of renal failure. Statistically significant (p<0.001) correlations were observed between both, RI and PI, and the serum creatinine level, creatinine clearance rate, and systolic and diastolic blood pressure measurements. Conclusion. Doppler indices reflect an increased RVR in the patients with chronic renal failure and correlate with the laboratory and clinical parameters, whereas RI and PI measurements offer no advantages over these parameters to predict the disease progress.

10.11.2023