Polifarmacija in neprimerno predpisovanje zdravil pri starostnikih v domovih starejših občanov
Polypharmacy and inappropriate drug prescribing in elderly nursing home residents

slovenian

2009

volume 78, issue 5

Aged   Comorbidity   drug   Drug Therapy, Combination   Homes For The Aged   Prescriptions, Drug

Slovensko zdravniško društvo
(Obvezni izvod spletne publikacije)

Background Polypharmacy and inappropriate drug use are common in nursing home residents, who are therefore at increased risk for potential adverse drug effects and drug interactions. In Slovenia, this is the first study of drug prescribing in elderly nursing home residents. Methods This study was cross-sectional, including 2040 elderly nursing home residents in 12 nursing homes in Slovenia. 2003 Beers criteria and ten most common drug interactions were used to determine potentially inappropriate prescriptions. Results The mean age was 82.0 years (SD 7.7 years), 1597 (78 %) were female patients. The mean number of regularly prescribed drugs was 5.8, 1032 (50.6 %) of patients were taking more than 6 drugs at once. Higher number of drugs were more often prescribed to female patients. Patients with dementia and fully dependant patients were prescribed less, and patients with depression and those who werepartially dependent in their daily activities were prescribed more drugs. 455 (22.3 %) residents had at least one inappropriately prescribed drug or combination of drugs. Male patients (p = 0.008), residents partially dependenton daily activities (p = 0.001) and patients with more prescribed drugs (p < 0.001) were more likely to have an inappropriate prescription. The most common inappropriate prescriptions were cyclooxigenase 2 non-selective nonsteroid anti-inflammatory drugs (NSAID), a prescription of NSAID, dipyridamole, ticlopidine or clopidogrel in patients with blood-clotting disorders or patients taking anticoagulants, a prescription of the combinationof digoxine and amiodarone, and the combination of an ACE inhibiting drugs and spironolactone. (Abstract truncated at 2000 characters)

18.05.2010