Insulinska rezistenca pri bolnicah s sindromom policističnih ovarijev
Insulin resistance in patients with polycystic ovary syndrome

slovenian

2009

volume 48, issue 3

Polycystic Ovary Syndrome    Insulin Resistance    Glucose Tolerance Test    Cholesterol    Lipoproteins, Ldl Cholesterol   Lipoproteins, Hdl Cholesterol   Triglycerides    Insulin    Blood    Blood Glucose    Body Weight    diagnostika

Društvo Medicinski razgledi
(Obvezni izvod spletne publikacije)

Polycystic ovary syndrome (PCOS) is the most common endocrine disease in fertile women. It is also dosely associated with insulin resistance (IR). The purpose of this trial was to investigate the value of dinical and laboratory IR markers routinely used in type 2 diabetes patients (DM2) for the diagnosis of IR in PCOS patients. The goal was to identify the most suitable marker for this condition out of the entire tested panel, which was comprised of ROMAm, intact proinsulin (IP), Sib index and IRIS II score. A total of 50 women with PCOS were recruited, along with 20 comparable, healthy women for the control group. HOMAIR values indicating IR (> 2) were seen in 26 patients (52 %). Patients with IR (based on HOMA'R) had significantly higher values for EMI (p <0.001), fasting glucose (4.7 0.6 vs. 4.2 0.3 nimo1!l, p = 0.001), insulin (16.8 6.2 vs. 7.1 2.1 jJU/ml, p