Sodobno medikamentno zdravljenje epilepsije pri odraslih
Modern medicamentous treatment of epilepsy in adults

slovenian

2006

volume 75, issue 6/7

Administration And Dosage   Anticonvulsants   Blood   drug   Drug Therapy   Epilepsy   Pharmacology   therapy

Slovensko zdravniško društvo
(Obvezni izvod spletne publikacije)

Background Several newer antiepileptic drugs (AEDs), i. e. vigabatrin, lamotrigine, gabapentin, topiramate, tiagabine, oxcarbazepine, levetiracetam, pregabalin and zonisamide have been introduced into clinicalpractice within the lastdecade. Most of these new drugs are atleast as effective as the older"AEDs (phenobarbital, phenytoin, valproic acid, carbamazepine) and in general, they seem to be better tolerated then the older drugs and have less side effects. The development of pharmaceutical industry has brought several new AEDs to clinical practice which increased a probability of therapeutic success, but also made treatment more complex. It is expected from the physician that she will know indications and contraindications for at least ISAEDs, their optimal titration, dosage, possible side effects and wide spectrum of interactions with other drugs. At this point advertisements of drug companies try to convince us aggressively about success of their own products. Conclusion This review article focuses on modern medicamentous treatment of adults with epilepsy, main characteristics of newer AEDs, conditionsm availability and statistics of their usage in Slovenia.

10.04.2014