Biološka zdravila pri multipli sklerozi
Biological medicinal products in the treatment of multiple sclerosis

slovenian

2015

volume 66, issue 1

therapy 

Slovensko farmacevtsko društvo
(Obvezni izvod spletne publikacije)

Therapeutic approaches to multiple sclerosis by means of modern biological medicinal products are based on altering the function of immune system. Interferon-ß and glatiramer acetate are basic biologicals in the treatment of RRMS ((relapsing-remitting multiple sclerosis) type of disease. Both biologicals are only partially suc- cesful, have important safety limitations and are effective in the earlier stages. Beside, monoclonal antibodies, suchas natalizumab, alemtuzumab, daclizumab, rituximab, ocrelizumab and of atumumab that act as specific and potent biological immunosupressive agents may offer considerable advantages over other biological and non-biological medicines. And finally, novel alternative methods, such as stem cell therapy or RNA interference therapy open a new frontier in the battle against the devastating effects of multiple sclerosis.

04.04.2017