{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-ZJS9BI0U/b25db258-3f3a-48ca-ab22-c80ddd417727/HTML","dcterms:extent":"35 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-ZJS9BI0U/52af378f-e015-4782-82e9-116421860c45/PDF","dcterms:extent":"190 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-ZJS9BI0U/445358c8-8946-4803-b7ea-b422f8a20d20/TEXT","dcterms:extent":"20 KB"}],"edm:TimeSpan":{"@rdf:about":"2002-2026","edm:begin":{"@xml:lang":"en","#text":"2002"},"edm:end":{"@xml:lang":"en","#text":"2026"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-ZJS9BI0U","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/urn:nbn:si:spr-py0w57lr"},{"@xml:lang":"sl","#text":"Zdravstveno varstvo"}],"dcterms:issued":"2005","dc:creator":["Franko-Kancler, Tatjana","Grmek-Košnik, Irena","Harlander, Tatjana","Kavčič, Martina","Ribič, Helena","Sarjanović, Ljudmila","Štrumbelj, Iztok","Žohar Čretnik, Tjaša"],"dc:format":[{"@xml:lang":"sl","#text":"številka:2"},{"@xml:lang":"sl","#text":"letnik:44"},{"@xml:lang":"sl","#text":"str. 74-79"}],"dc:identifier":["ISSN:0351-0026","COBISSID:1387237","URN:URN:NBN:SI:doc-ZJS9BI0U"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Inštitut za varovanje zdravja Republike Slovenije"},"dc:subject":[{"@xml:lang":"en","#text":"antibiotic"},{"@xml:lang":"sl","#text":"antibiotiki"},{"@xml:lang":"en","#text":"bacteria"},{"@xml:lang":"sl","#text":"bakterije"},{"@xml:lang":"sl","#text":"dihala"},{"@xml:lang":"sl","#text":"Haemophylus influenzae"},{"@xml:lang":"sl","#text":"odpornost"}],"dcterms:temporal":{"@rdf:resource":"2002-2026"},"dc:title":{"@xml:lang":"sl","#text":"Nacionalno spremljanje odpornosti pri sevih bakterije Haemophilus influenzae iz dihal v Sloveniji v letu 2003| Nation-wide surveillance of antimicrobial resistance of Haemophilus influenzae strains from respiratory tract, Slovenia, 2003|"},"dc:description":[{"@xml:lang":"sl","#text":"Objective: The authors determined the rate of antimicrobial resistance of Haemophylus influenzae strains isolated from the respiratory tract. Methods: In 2003, 746 H. influenzae strains were isolated from respiratory specimens ineight Slovene microbiological laboratories.The susceptibility of isolates toseven to ten antibiotics was tested by the disk susceptibility method, and the production of beta lactamase enzymes was determined using chromogenic nitrocephin. Results: All the strains tested were susceptible to levofloxacin,moxifloxacin and cefotaxime. The rate of resistance to ampicillinwas 12.7%: beta-lactamase enzyme was produced in 12.3% of strains, and 0.4% of strains were beta-lactamase negative-ampicillin resistant (BLNAR strains). The rate of resistance to amoxicillin and clavulanic acid was 0.5%, to cefaclor 0.8%, to trimethoprim-sulfamethoxazole 13.3%, to tetracycline 0.9%, to azitromycin 0.1% and to cefuroxime 0.5%. Notable differences in resistance rates were found between individual geographical areas and patient age groups. Conclusions: Surveillance of antibiotic susceptibility of respiratory bacteria plays a key role in assessing the prevalence of resistance and in tracking changes in antimicrobial susceptibility. On the basis of these data, modifications to the empirical therapy guidelines are made. In 2003, resistance of H. influenzae strains to penicillin increased in comparison to the previous year"},{"@xml:lang":"sl","#text":"Namen: Pri sevih bakterijske vrste Haemophylus influenzae, osamljenih iz dihalv letu 2003, so avtorji ugotavljali delež odpornih sevov. Metode: V letu 2003 so v osmih slovenskih mikrobioloških laboratorijih iz kužnin dihal osamili 746 sevov H. influenzae. Vsem sevom so z metodo difuzije antibiotika vagarju z diski določili občutljivost za sedem do deset izbranih antibiotikov.Da bi določili tvorbo encimov laktamaz beta, so vse seve testirali s kromogenim nitrocefinskim testom. Rezultati: Vsi sevi, ki so jih testirali z levofloksacinom, moksifloksacinom in cefotaksimom, so bili za naštete antibiotike občutljivi. Proti ampicilinu je bilo odpornih 12,7 % sevov: encime laktamaze beta je tvorilo 12,3 % sevov, 0,4 % je bilo sevov BLNAR (angl.: beta-lactamase negative-ampicillin resistant). Proti amoksicilinu s klavulansko kislino je bilo odpornih 0,5 % sevov, proti cefakloru 0,8 %, proti trimetoprimu s sulfametoksazolom 13,3 %, proti tetraciklinu 0,9 %, proti azitomicinu 0,1 % in proti cefuroksimu 0,5 %. Ugotovili so velike razlike v odpornosti sevov med regijami in manjše razlike pri različno starih preiskovanih bolnikih. Zaključek: Spremljanje odpornosti bakterij iz dihal je ključno za ugotavljanje prevalence odpornih sevov, določanje trendov odpornosti in je osnova za spremembe priporočil za izkustveno zdravljenje okužb dihal. V letu 2003 je v primerjavi z letom 2002 opaziti trend naraščanja odpornosti sevov H. influenzae proti ampicilinu"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-ZJS9BI0U","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-ZJS9BI0U"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-ZJS9BI0U/52af378f-e015-4782-82e9-116421860c45/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Inštitut za varovanje zdravja RS"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-ZJS9BI0U/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-ZJS9BI0U"}}}}