{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-XMZIIXEE/a71f9201-891d-4193-b1c6-d4400bbaa915/HTML","dcterms:extent":"20 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-XMZIIXEE/37e01d43-8f53-42fd-9d40-a10a9996acfc/PDF","dcterms:extent":"1946 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-XMZIIXEE/314fa7d1-343f-4caf-8e33-3af51b6409a4/TEXT","dcterms:extent":"15 KB"}],"edm:TimeSpan":{"@rdf:about":"1992-2025","edm:begin":{"@xml:lang":"en","#text":"1992"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-XMZIIXEE","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:SPR-WQVGMCSC"},{"@xml:lang":"sl","#text":"Acta dermatovenerologica Alpina, Pannonica et Adriatica"}],"dcterms:issued":"2008","dc:creator":["Aberer, W.","Kränke, Birger","Mayr-Kanhäuser, Sigrid"],"dc:format":[{"@xml:lang":"sl","#text":"letnik:17"},{"@xml:lang":"sl","#text":"številka:3"},{"@xml:lang":"sl","#text":"str. 139-143"}],"dc:identifier":["ISSN:1318-4458","COBISSID:24955097","URN:URN:NBN:SI:doc-XMZIIXEE"],"dc:language":"en","dc:publisher":{"@xml:lang":"sl","#text":"Slovene Welding Society"},"dc:subject":[{"@xml:lang":"en","#text":"Acne Vulgaris"},{"@xml:lang":"en","#text":"Administration, Topical"},{"@xml:lang":"sl","#text":"Akna navadna"},{"@xml:lang":"sl","#text":"akne"},{"@xml:lang":"en","#text":"antibiotic"},{"@xml:lang":"sl","#text":"antibiotiki"},{"@xml:lang":"en","#text":"Anti-Infective Agents, Local"},{"@xml:lang":"sl","#text":"Antiinfektivi lokalni"},{"@xml:lang":"en","#text":"Drug Therapy"},{"@xml:lang":"sl","#text":"rezistenca"},{"@xml:lang":"en","#text":"therapy"},{"@xml:lang":"sl","#text":"Zdravilo, lokalna uporaba"},{"@xml:lang":"sl","#text":"zdravljenje"}],"dcterms:temporal":{"@rdf:resource":"1992-2025"},"dc:title":{"@xml:lang":"sl","#text":"Efficacy of octenidine dihydrochloride and 2-phenoxyethanol in the topical treatment of inflammatory acne|"},"dc:description":{"@xml:lang":"sl","#text":"Background: With the increase in antibiotic-resistant strains of microorganisms in acne lesions, the search for alternative treatment methods has become important. We studied the efficacy of a combination of the antiseptic substances octenidine dihydrochloride and 2-phenoxyethanol (O/P) in mild to moderate inflammatory acne vulgaris. Methods: Thirty patients were instructed to apply O/P once or twice daily for a 6-week treatment period. Determination of efficacy included the numerical documentation of inflammatoryand non-inflammatory lesions within defined regions of the face bythe investigator, and photodocumentation of the clinical picture as well as the fluorescence pattern under Wood's light. Results: Twenty-four patients completed the study. The number of papules and pustules decreased more than 50% in seventeen and nineteen patients, respectively. Acne lesions worsened inonly one patient. Mild adverse reactions (erythema, burning, and scaling) were seen in two patients. Therefore, O/P was highly effective in treating inflammatory lesions of facial acne, but there was no essential efficacy in the non-inflammatory primary acne lesions. Conclusion: Topical O/P is a good and cost-effective alternative in the treatment of mild to moderate inflammatory acne lesions and may allow reduced application of anti-acne antibiotics to prevent development of resistance"},"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-XMZIIXEE","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-XMZIIXEE"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-XMZIIXEE/37e01d43-8f53-42fd-9d40-a10a9996acfc/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Združenje slovenskih dermatovenerologov"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-XMZIIXEE/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-XMZIIXEE"}}}}