116 KB7 KB199220252009Fernandes, Neil F.Lambert, W. ClarkMalliah, RajitRozdeba, PaulSchwartz, Robert A.Stitik, Todd P.številka:1letnik:18str. 28-30ISSN:1318-4458COBISSID_HOST:25731033URN:URN:NBN:SI:doc-XDOVV1XOenSlovene Welding SocietyActa dermatovenerologica Alpina, Pannonica et AdriaticaAdministration & DosageAdverse EffectsAged, 80 And OverEtiologyGlucocorticoidsGlukokortikoidiHerpes ZosterInjections, Intra-ArticularInjekcije intraartikularneMethylprednisoloneMetilprednizolonPathologyStarost 80 in večVirus ActivationVirusna aktivacijaHerpes zoster following intra-articular corticosteroid injection|Localized herpes zoster following intra-articular corticosteroid injection is remarkable. We describe an 80-year-old woman with severe osteoarthritis that received an intra-articular injection of 80 mg methylprednisolone in her knee,followed 1 day later by the appearance of linear unilateral vesicles and bullae on her leg in a dermatomal distribution adjacent to the injection site.The roofs of several blisters showed classic viral cytopathic effects forherpes including keratinocytes with multinucleation and margination of chromatin. Varicella zoster virus immunostaining revealed positive staining inthe keratinocytes. One plausible explanation is herpes zoster virus reactivation secondary to localized immunosuppression from corticosteroid injectionTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaZdruženje slovenskih dermatovenerologov