10 KB79 KB9 KB199220252007Drinovec, IgorKošnik, MitjaZidarn, Mihaelaštevilka:1letnik:16str. 31-33ISSN:1318-4458COBISSID:22699225URN:URN:NBN:SI:doc-WYVFCUFMenSlovene Welding SocietyActa dermatovenerologica Alpina, Pannonica et AdriaticaAgedAnafilaksijaAnaphylaxisBee VenomsČebelji strupiIgEImmunotherapyimunotefrapijaImunoterapijaKožni testiOsji strupipiki žuželkSkin TestsStarostnikistrupiWasp VenomsAnaphylaxis after Hymenoptera sting without detectable specific IgE|Current guidelines for venom immunotherapy suggest that immunotherapy should be performed only in patients with IgE mediated systemic reactions. However, opinions on the diagnosis and treatment of patients with systemic reactions inthe absence of IgE are quite varied. We present a patient with a history of atypical systemic reactions after a bee sting. Skin tests and specific IgE forbee venom were negative. We performed a sting provocation test in order to characterize the nature and mechanism of reaction. The provocation test was positive and mast cell activation was proved by tryptase elevation. We decidedto treat the patient with immunotherapy. After beginning immunotherapy we were able to detect specific IgE for bee venom in the serumTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaZdruženje slovenskih dermatovenerologov