{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-WNI8RZ9Y/f8d62afd-ea56-4dd3-bff1-28ab9ee64672/PDF","dcterms:extent":"146 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-WNI8RZ9Y/11730257-ac6c-4b25-9c0f-08f4ca9266ff/TEXT","dcterms:extent":"23 KB"}],"edm:TimeSpan":{"@rdf:about":"2002-2024","edm:begin":{"@xml:lang":"en","#text":"2002"},"edm:end":{"@xml:lang":"en","#text":"2024"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-WNI8RZ9Y","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:spr-1R5DVDOA"},{"@xml:lang":"sl","#text":"Informatica Medica Slovenica"}],"dcterms:issued":"2008","dc:creator":["Ferk, Polonca","Leskošek, Branimir"],"dc:format":[{"@xml:lang":"sl","#text":"številka:1"},{"@xml:lang":"sl","#text":"letnik:13"},{"@xml:lang":"sl","#text":"str. 33-40"}],"dc:identifier":["ISSN:1318-2129","COBISSID:24777945","URN:URN:NBN:SI:doc-WNI8RZ9Y"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko društvo za medicinsko informatiko"},"dc:subject":[{"@xml:lang":"sl","#text":"Aleli"},{"@xml:lang":"sl","#text":"Alleles"},{"@xml:lang":"sl","#text":"Breast Neoplasms"},{"@xml:lang":"sl","#text":"Citokrom P-450 CYP2D6"},{"@xml:lang":"sl","#text":"Cytochrome P-450 Cyp2d6"},{"@xml:lang":"sl","#text":"Dojka, novotvorbe"},{"@xml:lang":"sl","#text":"Drug Therapy"},{"@xml:lang":"sl","#text":"Farmakogenetika"},{"@xml:lang":"sl","#text":"farmakogenomika"},{"@xml:lang":"sl","#text":"genetika"},{"@xml:lang":"sl","#text":"Genotip"},{"@xml:lang":"sl","#text":"Genotype"},{"@xml:lang":"sl","#text":"Informacijski sistemi"},{"@xml:lang":"sl","#text":"informatika"},{"@xml:lang":"sl","#text":"Information Systems"},{"@xml:lang":"sl","#text":"Pharmacogenetics"},{"@xml:lang":"sl","#text":"Polimorfizem (genetika)"},{"@xml:lang":"sl","#text":"Polymorphism (Genetics)"},{"@xml:lang":"sl","#text":"Preživetje, analiza"},{"@xml:lang":"sl","#text":"Survival Analysis"},{"@xml:lang":"sl","#text":"Tamoksifen"},{"@xml:lang":"sl","#text":"Tamoxifen"}],"dcterms:temporal":{"@rdf:resource":"2002-2024"},"dc:title":{"@xml:lang":"sl","#text":"Farmakogenomika in informacijski izzivi| Pharmacogenomics and informatical challenges|"},"dc:description":{"@xml:lang":"sl","#text":"Pharmacogenomics is an interdisciplinary field which merges knowledge from pharmacology and genomics. Its basic aim is to find out how the unique genotype of an individual determines specific pharmacological responses. To beable to discover clinically relevant associations between the specific genotype and pharmacological response, huge amounts of data should be collected from different sources and further analyzed which is possible only by using suitable and effective informatics tools. In the paper a clinically relevant pharmacogenomic example is first presented and then contemporary informatics challenges are described"},"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-WNI8RZ9Y","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-WNI8RZ9Y"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-WNI8RZ9Y/f8d62afd-ea56-4dd3-bff1-28ab9ee64672/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko društvo za medicinsko informatiko"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-WNI8RZ9Y/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-WNI8RZ9Y"}}}}