146 KB23 KB200220242008Ferk, PoloncaLeskošek, Branimirštevilka:1letnik:13str. 33-40ISSN:1318-2129COBISSID:24777945URN:URN:NBN:SI:doc-WNI8RZ9YslSlovensko društvo za medicinsko informatikoInformatica Medica SlovenicaAleliAllelesBreast NeoplasmsCitokrom P-450 CYP2D6Cytochrome P-450 Cyp2d6Dojka, novotvorbeDrug TherapyFarmakogenetikafarmakogenomikagenetikaGenotipGenotypeInformacijski sistemiinformatikaInformation SystemsPharmacogeneticsPolimorfizem (genetika)Polymorphism (Genetics)Preživetje, analizaSurvival AnalysisTamoksifenTamoxifenFarmakogenomika in informacijski izzivi| Pharmacogenomics and informatical challenges|Pharmacogenomics is an interdisciplinary field which merges knowledge from pharmacology and genomics. Its basic aim is to find out how the unique genotype of an individual determines specific pharmacological responses. To beable to discover clinically relevant associations between the specific genotype and pharmacological response, huge amounts of data should be collected from different sources and further analyzed which is possible only by using suitable and effective informatics tools. In the paper a clinically relevant pharmacogenomic example is first presented and then contemporary informatics challenges are describedTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko društvo za medicinsko informatiko