{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-W9T8DUIC/c7124dbf-1fa0-4573-8d04-4e02e8d82ebd/PDF","dcterms:extent":"2624 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-W9T8DUIC/e272953d-8e00-4a0e-b25e-531374c8bd25/TEXT","dcterms:extent":"40 KB"}],"edm:TimeSpan":{"@rdf:about":"2005-2025","edm:begin":{"@xml:lang":"en","#text":"2005"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-W9T8DUIC","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:spr-8ER5ZBJN"},{"@xml:lang":"sl","#text":"Farmacevtski vestnik"}],"dcterms:issued":"2020","dc:creator":["Ahlin Grabnar, Pegi","Dreu, Rok","Gašperlin, Mirjana","German Ilić, Ilija","Gosenca Matjaž, Mirjam","Kocbek, Petra","Kristl, Julijana","Planinšek, Odon","Srčič, Stanko","Zupančič, Špela","Zvonar Pobirk, Alenka"],"dc:format":[{"@xml:lang":"sl","#text":"številka:1"},{"@xml:lang":"sl","#text":"letnik:71"},{"@xml:lang":"sl","#text":"str. 63-71"}],"dc:identifier":["ISSN:0014-8229","COBISSID_HOST:4898673","URN:URN:NBN:SI:doc-W9T8DUIC"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko farmacevtsko društvo"},"dc:subject":[{"@xml:lang":"sl","#text":"bolnikom prijazni dostavni sistemi"},{"@xml:lang":"sl","#text":"Dostavni sistemi"},{"@xml:lang":"sl","#text":"Farmacevtska tehnologija"},{"@xml:lang":"sl","#text":"Farmacevtske oblike"},{"@xml:lang":"sl","#text":"lipidni sistemi"},{"@xml:lang":"sl","#text":"nanozdravila"},{"@xml:lang":"sl","#text":"stabilni biofarmacevtiki"},{"@xml:lang":"sl","#text":"večenotne farmacevtske oblike"},{"@xml:lang":"sl","#text":"zdravila z vgrajeno kakovostjo"}],"dcterms:temporal":{"@rdf:resource":"2005-2025"},"dc:title":{"@xml:lang":"sl","#text":"Z razvojem sodobnih tehnologij in naprednih dostavnih sistemov do učinkovitejšega zdravljenja| Development of innovative technologies and advanced drug delivery systems for more efficient therapy|"},"dc:description":[{"@xml:lang":"sl","#text":"Development of an optimal drug delivery system is a key factor within development process of a medicine. In concordance with increasing complexity of active pharmaceutical ingredients and medical treatments, advanced drug delivery systems are implemented, contributing to the increased efficiency and prolonged life cycle of medicines. At the Department of Pharmaceutical Technology the contemporary trends in development of innovative delivery systems are successfully followed and expertise based solutions are provided for the challenges arising within industrially established technologies. The present paper represents our most valuable research achievements in the last ten years: development of patient-friendly drug delivery systems, implementation of modern technologies in manufacturing medicines by quality by design, technological approaches for improving solubility and bioavailability of active pharmaceutical ingredients, mukoaddevelopment of stable biopharmaceutics and nanocarriers, all for the purpose of more effective therapy"},{"@xml:lang":"sl","#text":"Razvoj optimalnega dostavnega sistema je pomemben dejavnik v celotnem procesu razvoja zdravila. Z naraščajočo kompleksnostjo novih zdravilnih učinkovin in postopkov zdravljenja postajajo tudi dostavni sistemi vse naprednejši, kar prispeva k večji učinkovitosti in podaljšanju življenjskega cikla zdravil. Na Katedri za farmacevtsko tehnologijo uspešno sledimo sodobnim trendom razvoja inovativnih dostavnih sistemov, z našo ekspertizo pa se učinkovito vključujemo tudi v reševanje perečih izzivov industrijsko že uveljavljenih tehnologij. V članku predstavljamo naše najpomembnejše raziskovalne dosežke predvsem v zadnjih desetih letih: razvoj bolnikom prijaznih dostavnih sistemov, uporaba sodobnih tehnologij za izdelavo zdravil z vgrajeno kakovostjo, pristopi za povečanje topnosti in biološke uporabnosti, razvoj stabilnih biofarmacevtikov ter nanodostavnih sistemov, vse z namenom učinkovitejšega zdravljenja"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-W9T8DUIC","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-W9T8DUIC"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-W9T8DUIC/c7124dbf-1fa0-4573-8d04-4e02e8d82ebd/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko farmacevtsko društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-W9T8DUIC/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-W9T8DUIC"}}}}