107 KB0 KB201020252010Bizjak, MarijaPreveden, Ružicaštevilka:1letnik:17str. 10-18ISSN:1318-4423COBISSID:26886361URN:URN:NBN:SI:doc-W8AU1ZX7slZdruženje pediatrov SlovenijeZdruženje specialistov šolske in visokošolske medicine SlovenijeSlovenska pediatrijadermatologijadiagnostikahemangiomikožne spremembeSkin NeoplasmszdravljenjeInfantilni hemangiomi| Infantile hemangiomas|Classification: A number of different congenital vascular lesions occur in theskin. A simple classification, consisting of two groups, hemangiomas of infancy (HI) and vascular malformations, is based mostly on history and physical examination. Pathogenesis: HI are benign neoplasms that result from rapid proliferation of endothelial cells. Vascular spaces may have features ofcapillaries, venules, and arterioles. Early hemangiomas are highly cellular.Progressive interstitial fibrosis occurs during regression. Clinic alfeatures: HI demonstrate a typical growth pattem characterized by early proliferation followed by gradual, spontaneous involution. Diagnosis: Superficial and mixed HI are usually diagnosed based upon their characteristicclinical features. Hemangioma precursors may sometimes be misdiagnosed as capillary malformations or telangiectasias. Deep lesions provide a greater challenge and radiographic evaluation may be helpful in clarifying the diagnosis. Therapy: The choice of treatment, if any, depends onmultiple factors and must be tailored to each individual patient. Unfortunately, there is no universal approach to their management. Conclusions: HI can manifest themselves in the form ofbenign or dangerous tumours, which must be recognizedTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaDruštvo za pomoč otrokom s presnovnimi motnjami