1746 KB13 KB199220252025Coutada, AndreiaCoutada, AndreiaDi Loreto, CarlaLuzar, BoštjanMatjašič, Alenkaletnik:34številka:iss. ahead of printstr. 1-6DOI:10.15570/actaapa.2025.3ISSN:1318-4458COBISSID_HOST:233228547URN:URN:NBN:SI:doc-VCN20SWBenSlovene Welding SocietyActa dermatovenerologica Alpina, Pannonica et Adriaticacase reportcutaneous spindle cell neoplasmkinase fusion neoplasmkinazna fuzijska novotvorbakožna neoplazma vretenastih celicNTRK3prikaz primerasoft tissue tumortumor mehkega tkivaNTRK3-rearranged spindle cell neoplasm of the skin| diagnostic pitfalls of an emerging entity, a case report|Neurotrophic tyrosine receptor kinase-rearranged spindle cell neoplasms (NTRK-RSCNs) are an emerging category of rare soft tissue tumors recently recognized by the World Health Organization Classification of Soft Tissue and Bone Tumours. NTRK-RSCNs mostly affect the superficial soft tissues of the extremities and trunk, and they can occur across a broad age range. These tumors exhibit a wide morphologic spectrum, often mimicking other mesenchymal tumors. Recognition of NTRK-RSCNs is crucial for targeted therapy in selected cases, given the recent approval of kinase inhibitors. We describe the case of a 55-year-old male with an NTRK-RSCN located on the arm, harboring the novel fusion partner PPFIBP1::NTRK3, while providing additional clinical and morphological characteristics of this rare entityTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaZdruženje slovenskih dermatovenerologov