1488 KB8 KB199220251999Doria, A...Nobile, C...Pauluzzi, P...Trevisan, G...številka:3letnik:8str. 119-121COBISSID_HOST:10702297ISSN:1318-4458URN:URN:NBN:SI:doc-UFO9J9UVenSlovene Welding SocietyActa dermatovenerologica Alpina, Pannonica et AdriaticaChildCholecalciferolDrug therapyOintmentsPsoriasisTreatment outcomeCalcipotriol cream in childhood psoriasis|Background. Calcipotriol ointment, a vitamin D3 synthetic derivative, confirmed its efficacy and its high safety when employed in the treatment of adult psoriasis and sometimes in children, too. Cream seems to be the most clinically appropriate choice to treat particularly delicate and easily irritable skins. Methods. Nine enrolled psoriatic children (mean age 10.1 + 4.1 SD years) were treated with calcipotriol cream (50 ug/g) 2 application/dayduring six consecutive weeks. PASI (Psoriasis Area and SeverityIndex) was evaluated at fortnightly visits. Furthermore, routine laboratory parameters were controlled before and at the end of the treatment. Results. Mean PASI was 2.2+0.5 (SEM) at the baseline, and decreased to 0.7+0.5after six weeks of treatment; a 65.9% reduction was seen. Calcipotriol cream showed an excellent safety, as the lack of irritant cutaneous adverse reactions and/or laboratory parameters alterations. Conclusion. Our clinical experience suggests Calcipotriol cream as one of the most important therapeutic choice in psoriasisTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaZdruženje slovenskih dermatovenerologov