{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-SYIP7LAY/3dbd3508-3ad5-4d4f-b803-dd57d4f455b4/PDF","dcterms:extent":"598 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-SYIP7LAY/956eae17-57e4-4845-8fa2-26999be94592/TEXT","dcterms:extent":"68 KB"}],"edm:TimeSpan":{"@rdf:about":"1992-2025","edm:begin":{"@xml:lang":"en","#text":"1992"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-SYIP7LAY","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:spr-DJTGDZOW"},{"@xml:lang":"sl","#text":"Psihološka obzorja (Ljubljana)"}],"dcterms:issued":"2022","dc:creator":["Bregar, Janez","Kreft, Ivana","Mlinarič Lešnik, Vesna"],"dc:format":[{"@xml:lang":"sl","#text":"številka:letn. 31"},{"@xml:lang":"sl","#text":"str. 33-49"}],"dc:identifier":["DOI:10.20419/2022.31.548","COBISSID:110152195","ISSN:2350-5141","URN:URN:NBN:SI:doc-SYIP7LAY"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Društvo psihologov Slovenije"},"dc:subject":[{"@xml:lang":"sl","#text":"kognicija"},{"@xml:lang":"sl","#text":"kognitivne sposobnosti"},{"@xml:lang":"sl","#text":"otroci"},{"@xml:lang":"sl","#text":"razvoj otroka"},{"@xml:lang":"sl","#text":"splošna anestezija"}],"dcterms:temporal":{"@rdf:resource":"1992-2025"},"dc:title":{"@xml:lang":"sl","#text":"Učinki splošne anestezije na kognitivne sposobnosti pri otrocih| a review| pregledni članek| The effects of general anesthesia on cognition in children|"},"dc:description":[{"@xml:lang":"sl","#text":"The theoretical models of pathophysiological mechanisms responsible for cognitive sequelae after general anesthesia are multifactorial, as most general anesthetics impact several neurotransmitter systems of the nervous system. Animal models show, that during periods of maturation neurons are more susceptible to damage from general anesthetics, while mature neurons are largely unaffected. Research done in children is mostly based on retrospective studies and their results tend to show that general anesthesia mostly impairs cognitive abilities, that are functionally under intense development at the time (for example speech between the ages of 2 and 4) although current data does not allow for definite conclusions about cognitive functions being affected. Most reported cognitive deficits are subclinical but tend to be present across a wide range of cognitive functions. However, no effect of general anesthesia on general intelligence has been noted. Cognitive consequences after general anesthesia in children are diverse and can be intertwined with the underlying condition that led to the use of general anesthesia. Current clinical guidelines suggest general anesthesia in children should be used in the lowest and shortest effective dose. The consensus is that withholding necessary treatments under general anesthesia would bring more harm than exposure to general anesthesia, therefore in clinical practice attention must be given to potential cognitive deficits in children who underwent procedures under general anesthesia"},{"@xml:lang":"sl","#text":"Teoretični modeli nastanka kognitivne motnje po splošni anesteziji vključujejo več dejavnikov, saj ima večina splošnih anestetikov širok razpon delovanja na številne nevrotransmiterske sisteme v osrednjem živčevju. Raziskave na živalih nakazujejo, da so nevroni v fazi celičnega razvoja bolj občutljivi na škodljive učinke splošnih anestetikov v primerjavi z zrelimi nevroni. Raziskave, ki so bile izvedene na otrocih, večinoma temeljijo na retrospektivnih podatkih, rezultati pa nakazujejo, da splošna anestezija najbolj prizadene sposobnosti, ki se funkcionalno v tistem obdobju najintenzivnejše razvijajo (npr. govor med 2. in 4. letom starosti), vendar pa trenutno ni mogoče podati povsem jasnega zaključka glede učinkov na posamezne kognitivne funkcije. Večina ugotovljenih primanjkljajev je subkliničnih, kažejo pa se na širokem področju kognitivnih sposobnosti, pri splošnih intelektualnih sposobnostih pa primanjkljajev niso dokazali. Kognitivne posledice splošne anestezije pri otrocih so lahko raznolike in se prepletajo s samim vzrokom za uporabo splošne anestezije. Klinične smernice svetujejo, da se splošna anestezija pri otrocih uporablja v čim nižjem odmerku in traja čim krajši čas. Splošni konsenz je, da bi kljub morebitnemu tveganju za kognitivno oškodovanost, izostanek od potrebnih zdravstvenih posegov prinesel več negativnih posledic kot splošna anestezija, zaradi česar pa je iz psihološkega vidika smiselno, da smo pri obravnavi pozorni tudi na morebitne težave otrok, ki so bili izpostavljeni medicinskim posegom pod splošno anestezijo"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-SYIP7LAY","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-SYIP7LAY"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-SYIP7LAY/3dbd3508-3ad5-4d4f-b803-dd57d4f455b4/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Društvo psihologov Slovenije"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-SYIP7LAY/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-SYIP7LAY"}}}}