360 KB35 KB200820252013Letonja, MitjaNikolajević-Starčević, JovanaPetrovič, DanijelŠantl-Letonja, Marijaštevilka:1letnik:6str. 33-44ISSN:1855-5640COBISSID:24153912URN:URN:NBN:SI:doc-SYCGQGRXenMedicinska fakultetaActa medico-biotechnicacarotid atherosclerosisdiabetes mellituskarotidna aterosklerozamarkers of atherosclerosismetabolni sindromsladkorna bolezenUltrasonographic and classical risk factors of carotid atherosclerosis in patients with type-2 diabetes mellitus| Ultrazvočni in klasični dejavniki tveganja karotidne ateroskleroze pri bolnikih s sladkorno boleznijo tipa 2|Purpose: We determined the prevalence of the clinical and biochemical risk factors as well as the extent of atherosclerosis in carotid arteries in patients with diabetes mellitus type 2(DMT2). Methods: A total of 289 subjects with DMT2 and 157 healthy subjects were enrolled in this prospective cross-sectional study. Leveles of total cholesterol, high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), triglycerides, fasting, blood glucose, fribrinogen, and high-sensitivity C-reactive protein (hsCRP) were measured using standard biochemical methods. Carotid atherosclerosis was assessed by ultrasonography. Intima media thickness (IMT), plaque type and plaque score were also determinedNamen: V raziskavi smo želeli ugotoviti prevalenco biokemičnih in kliničnih dejavnikov tveganja ter razširjenost ateroskleroze karotidnih arterij pri bolnikih s sladkorno boleznijo tipa 2 (SBT2). Metode: V prospektivno presečno študijo smo vključili 289 bolnikov s SBT2 in 157 zdravih preiskovancev. Anamnestične in klinične podatke smo zajeli z enotnim vprašalnikom. Vrednosti celokupnega holesterola, LDL in HDL holesterola, trigliceridov, glukoze, fibrinogena ter visokoobčutljivega C-reaktivnega proteina (CRP) smo določili s standardnimi biokemijskimi postopki. Aterosklerozo karotidnih arterij smo ocenili z ultrazvokom in opredelili debelino intime in medije, tip plakov ter seštevek plakovTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaUniverza v Mariboru, Medicinska fakulteta