326 KB37 KB200520252025Kreft, Samoštevilka:3letnik:76str. 177-183ISSN:0014-8229COBISSID_HOST:245880323URN:URN:NBN:SI:doc-SILHYPI4slSlovensko farmacevtsko društvoFarmacevtski vestnikblack cohoshcimicifugafitoestrogeniherbal medicinesisoflavonesizoflavonimenopauseMenopavzaphytoestrogensZdravilne rastlineZdravilne rastline pri menopavzi| Medicinal plants in menopause| klinična učinkovitost in varnost| clinical eficacy and safety|Menopause is a natural process that can cause various symptoms, such as hot flushes, night sweats, irritability, and difficulty concentrating. While hormone therapy is effective, it is not suitable for all women, leading to the frequent use of herbal preparations. This article provides a detailed analysis of the therapeutic effects and safety of black cohosh and phytoestrogen-containing plants such as soy, red clover, hops, and fenugreek. Extensive clinical studies and meta-analyses indicate the effectiveness of black cohosh in alleviating menopausal symptoms. Similarly, meta-analyses confirm the effects of isoflavones from soy and red clover, while findings on hops and fenugreek remain less conclusive. The European Medicines Agency recognizes black cohosh as scientifically proven to be effective and safe, while other plants are currently not officially recommended for managing menopausal symptomsV obdobju pred menopavzo lahko nastopijo simptomi, kot so vročinski oblivi, nočno potenje, razdražljivost in težave s koncentracijo. Čeprav je hormonsko zdravljenje učinkovito, za nekatere ženske ni primerno, zato se pogosto uporabljajo tudi rastlinski pripravki. Članek podrobno analizira terapevtske učinke in varnost cimicifuge ter rastlin s fito - estrogeni, kot so soja, črna detelja, hmelj in sabljasti triplat. Obsežne klinične raziskave in metaanalize cimicifuge kažejo na njeno učinkovitost pri lajšanju menopavznih simptomov. Prav tako metaanalize potrjujejo učinke izoflavonov iz soje in črne detelje, ugotovitve pri hmelju in sabljastem triplatu pa so manj temeljite. Evropska agencija za zdravila priznava cimicifugo kot znanstveno dokazano učinkovito in varno, medtem ko drugih rastlin za namen lajšanja menopavznih simptomov še ne priporočaTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko farmacevtsko društvo