204 KB0 KB200420252007Žgur-Bertok, Darjaštevilka:1letnik:90str. 17-24ISSN:1581-9175COBISSID:2214280URN:URN:NBN:SI:doc-QYI5C0P8enUniverza v Ljubljani, Biotehniška fakultetaActa agriculturae Slovenicabakterijefenotipska heterogenostgenotipmikrobiologijaPhenotypic heterogeneity in bacterial populations| Fenotipska heterogenost v bakterijskih populacijah|Genetically uniform bacterial cells exhibit heterogeneity such as intrapopulation differences in metabolism as well as variation in growth rate. Additionally, phenotypic heterogeneity in more complex developmental processes where a portion of a population performs specialized functions has been described. Heterogeneity within populations of bacterial cells ensures that a small fraction of the population is prepared to survive adverse environmental conditions. Phenotypic heterogeneity is mediated by two mechanisms: (i) genotypic alterations such as, mutations and rearrangements of specific DNA fragments or (ii) epigenetic phenomenon. Here examples of genotypic as well as epigenetically regulated phenotypic heterogeneity from several bacterial species are presentedGenetsko enake bakterijske celice izkazujejo heterogenost kot sta npr., znotraj populacijske razlike v metabolizmu in hitrosti rasti. Poleg tega so opisani primeri fenotipske heterogenosti zapletenih procesov razvoja pri katerih del populacije vrši posebne naloge. Heterogenost znotraj populacij bakterijskih celic zagotavlja, da je majhen del populacije pripravljen na morebitne neugodne pogoje okolja. Fenotipsko heterogenost posredujeta dva mehanizma: (i) genotipske spremembe kot so mutacije in prerazporeditve določenih fragmentov DNA ali (ii) epigenetski pojavi. V pričujočem prispevku so opisani primeri genotipske kakor tudi epigenetsko uravnane fenotipske heterogenosti nekaterih vrst bakterijTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaUniverza v Ljubljani, Biotehniška fakulteta