118 KB82 KB46 KB200220262008Rus, PrimožRus, Rina10 straništevilka:2letnik:47str. 89-98ISSN:0351-0026COBISSID:2029797URN:URN:NBN:SI:doc-QRZN1NAKslInštitut za varovanje zdravja Republike SlovenijeZdravstveno varstvoantioksidantiantioxidantkoencim Q10stranski učinkitherapyubikinonzdravljenjeKoencim Q 10| Coenzyme Q 10|Coenzyme Q 10 (CoQ), also known as ubiquinone, is a vitamin-like substance. It is important in adenosine triphosphate (ATP) synthesis in mitochondria and t is an effective antioxidant. The deficiency of CoQ is due to insuffcient dietary intake of CoQ, impairment in its biosynthesis, or excessive utilization of CoQ by the body. The dominant sources of CoQ in man are biosynthesis and dietary intake. The paper describes the role of CoQ in the prevention and treatment of cardiovascular diseases, migraine, mitochondrial and other diseases. Drug interactions, dosage and side effects observed duringCoQ treatment are describedKoencim Q 10 (KoQ), poznan tudi kot ubikinon, je po načinu delovanja podoben vitaminom. Pomemben je pri sintezi adenozin trifosfata (ATP) v mitohondrijih in je učinkovit antioksidant. Pomanjkanje KoQ v telesu je posledica premajhnega vnosa s hrano, motnje v biosintezi ali pa v povečanih potrebah organizma. V telesu nastaja v procesu biosinteze, del pa ga zaužijemo tudi s hrano. Članek obravnava pomen KoQ pri preprečevanju in zdravljenju kardiovaskularnih bolezni, migrene, mitohondrijskih in drugih bolezni. Opisane so interakcije z različnimi zdravili, odmerjanje in stranski učinki zdravljenja s KoQTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaInštitut za varovanje zdravja RS