{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-NS7G76KK/8119e89d-8c99-4e93-bcd1-c30dcdfbd8bf/PDF","dcterms:extent":"3475 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-NS7G76KK/bf8b2713-24dc-4e3c-883a-b2a4a2c48a13/TEXT","dcterms:extent":"19 KB"}],"edm:TimeSpan":{"@rdf:about":"1992-2025","edm:begin":{"@xml:lang":"en","#text":"1992"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-NS7G76KK","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:SPR-WQVGMCSC"},{"@xml:lang":"sl","#text":"Acta dermatovenerologica Alpina, Pannonica et Adriatica"}],"dcterms:issued":"2002","dc:creator":["Blizanowska, A...","Noworolska, A...","Szepietowki, J... C.","Wasik, A..."],"dc:format":[{"@xml:lang":"sl","#text":"številka:1"},{"@xml:lang":"sl","#text":"letnik:11"},{"@xml:lang":"sl","#text":"str. 15-20"}],"dc:identifier":["ISSN:1318-4458","COBISSID_HOST:14769113","URN:URN:NBN:SI:doc-NS7G76KK"],"dc:language":"en","dc:publisher":{"@xml:lang":"sl","#text":"Slovene Welding Society"},"dc:subject":[{"@xml:lang":"sl","#text":"Blood"},{"@xml:lang":"sl","#text":"Dermatitis atopični"},{"@xml:lang":"sl","#text":"Dermatitis, atopic"},{"@xml:lang":"sl","#text":"E-selectin"},{"@xml:lang":"sl","#text":"E-selektin"},{"@xml:lang":"sl","#text":"Ige"},{"@xml:lang":"sl","#text":"Psoriasis"},{"@xml:lang":"sl","#text":"Psoriaza"}],"dcterms:temporal":{"@rdf:resource":"1992-2025"},"dc:title":{"@xml:lang":"sl","#text":"Comparison of soluble E-selectin serum levels in two chronic inflammatory skindiseases| atopic dermatitis and psoriasis|"},"dc:description":{"@xml:lang":"sl","#text":"Background: Atopic dermatitis and psoriasis are common chronic cutaneous diseases of different pathogenetic aspects. Atopic dermatitis is considered asTh-2 and psoriasis as Th-1 type dermatosis, and this difference may lead to different expression of adhesion molecules. Objectives: This study was undertaken to evaluate soluble E-selectin serum levels in atopic dermatitis and psoriasis and to correlate its expression with the disease's severity. Material and methods: 16 patients suffering from atopic dermatitis, 20 psoriatic patients and 20 healthy individuals (control group) were included into the study. Soluble E-selectin serum levels were measured by ELISA using commercially available kits (R&D Systems). Severity of atopic dermatitis was assessed according to SCORAD and of psoriasis by PASI score. Results: The average serum level of soluble E-selectin in atopic dermatitis patients was 76.6t41.7 ng/ ml and did not significantly differ from that in psoriatic patients - 60.9ž33.2 ng/ml. Soluble E-selectin serum levels both in atopic dermatitis and psoriasis were significantly increased (p<0.0002 and p<0.0005, respectively) compared to the control group, 28.7ž9.5 ng/ml. Significant correlations (p<0.02) were found between soluble E-selectin serum levels and severity of atopic dermatitis and psoriasis. Conclusion: The enhanced endothelial activity (similar degree of activation) is a characteristic phenomenon for atopic dermatitis and psoriasis. The serum expression of soluble E-selectin could be used as a marker of disease's activity"},"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-NS7G76KK","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-NS7G76KK"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-NS7G76KK/8119e89d-8c99-4e93-bcd1-c30dcdfbd8bf/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Združenje slovenskih dermatovenerologov"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-NS7G76KK/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-NS7G76KK"}}}}