{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-NRZOZDJ2/87ab80c5-d29f-4f44-862c-e68d7b18aef7/PDF","dcterms:extent":"292 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-NRZOZDJ2/f89346a6-6940-4e5e-a60f-0483ae4bee83/TEXT","dcterms:extent":"34 KB"}],"edm:TimeSpan":{"@rdf:about":"1992-2025","edm:begin":{"@xml:lang":"en","#text":"1992"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-NRZOZDJ2","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:SPR-WQVGMCSC"},{"@xml:lang":"sl","#text":"Acta dermatovenerologica Alpina, Pannonica et Adriatica"}],"dcterms:issued":"2006","dc:creator":["Kazanowska, Bernarda","Reich, Adam","Wróbel, Grazyna"],"dc:format":[{"@xml:lang":"sl","#text":"letnik:15"},{"@xml:lang":"sl","#text":"številka:4"},{"@xml:lang":"sl","#text":"str. 158-168"}],"dc:identifier":["ISSN:1318-4458","COBISSID_HOST:22327257","URN:URN:NBN:SI:doc-NRZOZDJ2"],"dc:language":"en","dc:publisher":{"@xml:lang":"sl","#text":"Slovene Welding Society"},"dc:subject":[{"@xml:lang":"en","#text":"Diagnosis"},{"@xml:lang":"sl","#text":"Kožne manifestacije"},{"@xml:lang":"sl","#text":"Kožne novotvorbe"},{"@xml:lang":"en","#text":"Lymphoma, Non-Hodgkin's"},{"@xml:lang":"en","#text":"Neoplasm Staging"},{"@xml:lang":"sl","#text":"Novotvorba, stadij"},{"@xml:lang":"en","#text":"Pathology"},{"@xml:lang":"sl","#text":"Preživetje, analiza"},{"@xml:lang":"en","#text":"Retrospective Studies"},{"@xml:lang":"sl","#text":"Retrospektivne študije"},{"@xml:lang":"en","#text":"Skin Manifestations"},{"@xml:lang":"en","#text":"Skin Neoplasms"},{"@xml:lang":"en","#text":"Survival Analysis"},{"@xml:lang":"en","#text":"Therapy"}],"dcterms:temporal":{"@rdf:resource":"1992-2025"},"dc:title":{"@xml:lang":"sl","#text":"Skin involvement in highly malignant non-Hodgkin lymphomas of childhood and adolescence|"},"dc:description":{"@xml:lang":"sl","#text":"Objective: The aim of this study was to demonstrate the clinical spectrum of highly malignant cutaneous non-Hodgkin lymphoma (NHL) in children and to define the outcome among these patients. Material and methods: A retrospectiveanalysis of children with NHL treated at Polish oncology centers was carried out in order to determine patients with skin involvement. Thirteensubjects with primary and 4 with secondary cutaneous NHL were studied.The diagnosis of NHL was based on histological and immunohistochemicalexamination of skin biopsy. Results: Nine of 13 cases of primary cutaneous NHL presented as a tumors. Other manifestations were as follows: hard infiltration, edema of subcutaneous tissue, maculopapular lesions, and generalized erythroderma. The mean time between the first cutaneous symptoms and diagnosis of NHL was 5.6 +_ 3.3 months. Secondary cutaneous lesions during the course of NHL were described as maculopapular or nodular eruption. In addition, 2 subjects had generalized ichthyosis. Among patients with primary cutaneous NHL, 11 (84.6%) subjects are still alive without any signs of the disease. Two children (15.4°/o) died. In patients with secondary skin involvement during the course of NHL only one child is still alive with a residual tumor mass in the mediastinum. The estimated 5-year overall survival for primary cutaneous NHL was significantly better than for individuals with secondary cutaneous NHL (p = 0.02). Conclusions: Primary cutaneous NHL has a relatively favorable prognosis. On the other hand,cutaneous metastases of extracutaneous NHL seem to be a poor prognostic factor"},"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-NRZOZDJ2","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-NRZOZDJ2"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-NRZOZDJ2/87ab80c5-d29f-4f44-862c-e68d7b18aef7/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Združenje slovenskih dermatovenerologov"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-NRZOZDJ2/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-NRZOZDJ2"}}}}