3450 KB19 KB199220251995Cagnoni, M... L.Lotti, T...številka:1letnik:4str. 13-18ISSN:1318-4458COBISSID_HOST:3683545URN:URN:NBN:SI:doc-L7AG3UIWenSlovene Welding SocietyActa dermatovenerologica Alpina, Pannonica et AdriaticaConnective tissue diseasesScleroderma, systemicSkin diseasesThe skin in systemic sclerosis|Systemic sclerosis is a systemic disease of unknown etiology which has both cutaneous and systemic manifestations. This disorder is often preceded or accompanied by Raynaud's syndrome. Patients affected by chronic systemic sclerosis may present many cutaneous manifestations like pigmentary changes and vascular lesions including panniculitis, erythema nodosum, livedo reticularis, atrophie blanche or ulcerations that are often indicative of a specific phase of the disease. In very rare cases systemic sclerosis may occur without any cutaneous symptoms, while more frequently patients present different pattern of cutaneous involvement. Cutaneous involvement has been divided into three groups: the first group is characterized by an involvement of acral regions, the second group includes disorders which start distally and the third group is characterized by generalized cutaneous sclerosisTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaZdruženje slovenskih dermatovenerologov