258 KB52 KB199420252011Flašker, AjdaRituper, BoštjanZorec, Robertštevilka:4letnik:50str. 403-417ISSN:0025-8121COBISSID:29425113URN:URN:NBN:SI:doc-JI0ULYPYslMedicinski razglediMedicinski razglediBotulismBotulizemcelicecelična membranaCholesterolDigliceridiDiglyceridesEksocitozaExocytosisFatty Acids, UnsaturatedFosfatidilinozitol 4,5-difosfatfuzijaHolesterollipidiMaščobne kisline nezasičeneMembrana, zlitjeMembrane FusionMembrane LipidsMembrane ProteinsMembranske beljakovineMembranski lipidiNiemann-Pick DiseaseOculocerebrorenal SyndromeOkulocerebrorenalni sindromPhosphatidylinositol 4,5-DiphosphateSfingozinSphingosineVpogled v uravnavano eksocitozo| Insight into regulated exocytosis| role of lipids| vloga lipidov|Exocytosis, part of which is the merger of the vesicle and the plasma membrane, is characteristic for eukaryotic cells, which engage this process ina myriad of cell functions. For a long time it was believed that exocytosis was predominantly regulated by proteins, a view referred to as 'proteocentric'. Only recently it was shown that many oflipids, previously considered as passive cell membrane components, also play vital roles in regulation of exocytosis. Among others, such lipids are phosphatidylinositol-4,5-biphosphate, diacylglycerol, polyunsaturated fatty acids, sphingosine and cholesterol. Much like proteins, lipids act at various points in the process and influence exocytosis in various ways. The goal of this article is to highlight the role of lipids in exocytosisTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaDruštvo Medicinski razgledi