4643 KB18 KB199220251998Korošec, Ladkoštevilka:3/4letnik:7str. 145-149+151ISSN:1318-4458COBISSID:8099801URN:URN:NBN:SI:doc-JBRMSV3NenSlovene Welding SocietyActa dermatovenerologica Alpina, Pannonica et AdriaticaAdministration, oralAllylamineAntifungal agentsdermatologijaDermatomycosesDrug therapyfarmakokinetikaFluconazoleItraconazoleKetoconazolekožne boleznimikozeOnychomycosisPharmacokineticsTherapeutic usezdravljenjeThe pharmacokinetic properties of current systemic antifungal agents|Human fungal infections have increased dramatically and are difficult to treat. The spread of HIV/AIDS infection, the use of immunosuppressive drugs and broad-spectrum antibiotics have contributed to the spread of fungal infections. Spontaneous remissions are rare, and recurrence after treatment iscommon. The pharmacotherapy of the fungal diseases has been revolutionized by the introduction of the relatively non-toxic oral azoles. The systemic treatment with the new antifungal agents - fluconazole, itraconazole, and terbinafine - and the knowledge of their pharmacological and pharmacokinetic properties make possible the pulse therapy in the treatment of the fungal infestions. This will be of great benefit for patients from pharmacological aswell as pharmacoeconomic aspectsTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaZdruženje slovenskih dermatovenerologov