11 KB158 KB11 KB199220252006Bonači-Nikolić, BrankaMilinković, MirjanaNikolić, Miloš M.Skiljević, Dušanletnik:15številka:3str. 131-134ISSN:1318-4458COBISSID:21833177URN:URN:NBN:SI:doc-IN7X3KDIenSlovene Welding SocietyActa dermatovenerologica Alpina, Pannonica et AdriaticaAgedDiagnosiskožne bolezniKožne novotvorbelimfomLimfom velikocelični, Ki-1Lymphoma, Large-Cell, Ki-1novotvorbePathologySkin NeoplasmsStarostnikitumorRegressing anaplastic CD30-positive large-cell lymphoma of the skin|Originally believed to be of histiocytic origin, regressing primary cutaneous anaplastic large-cell lymphoma is a CD30 (Ki 1) positive T-cell lymphoma with histologic high grade malignancy, but with an often favorable clinical course with regression of individual lesions. We present a case of a 69-year-old white woman with an 8-month history of noduloulcerative lesions on her right lower leg, otherwise in good general health. The clinical, histologic, and immunohistochemical findings pointed to CD30 positive primary cutaneous anaplastic large-cell lymphoma. There were no signs of generalization, lymph node or internal organ involvement. After 2 years of activity, the disease regressed. During the 10-year follow-up period, no signs of disease reactivation were noted. Accurate recognition of this lymphoma is important toavoid unnecessary aggressive treatmentsTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaZdruženje slovenskih dermatovenerologov