{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-H4I18EGD/6f2-b82c3e1ead-fadbd4b-117044995f1f-/PDF","dcterms:extent":"337 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-H4I18EGD/5877d240-2da9-4e00-ba03-dd6f46eccdc8/TEXT","dcterms:extent":"31 KB"}],"edm:TimeSpan":{"@rdf:about":"2021-2024","edm:begin":{"@xml:lang":"en","#text":"2021"},"edm:end":{"@xml:lang":"en","#text":"2024"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-H4I18EGD","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:spr-07XDMEIG"},{"@xml:lang":"sl","#text":"Laboratorijska medicina"}],"dcterms:issued":"2021","dc:creator":["Dolžan, Vita","Goričar, Katja","Levstek, Tina","Podkrajšek, Tisa","Sotlar, Inge","Trebušak Podkrajšek, Katarina"],"dc:format":[{"@xml:lang":"sl","#text":"številka:3"},{"@xml:lang":"sl","#text":"str. 76-84"}],"dc:identifier":["ISSN:2670-4463","COBISSID:75086083","URN:URN:NBN:SI:doc-H4I18EGD"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko združenje za klinično kemijo in laboratorijsko medicino"},"dc:subject":[{"@xml:lang":"sl","#text":"ACTN3"},{"@xml:lang":"en","#text":"female football players"},{"@xml:lang":"sl","#text":"genotipizacija"},{"@xml:lang":"sl","#text":"nogometašice"},{"@xml:lang":"en","#text":"sports injuries"},{"@xml:lang":"sl","#text":"športne poškodbe"}],"dcterms:temporal":{"@rdf:resource":"2021-2024"},"dc:title":{"@xml:lang":"sl","#text":"Sprememba p.R577X gena ACTN3 (rs1815739) je povezana s pojavnostjo poškodb slovenskih nogometašic| Variant p.R577X (rs1815739) in ACTN3 gene is associated with frequency of injuries in Slovenian female football players|"},"dc:description":{"@xml:lang":"sl","#text":"Alpha-actinin-3 is a protein expressed in fast-twitch (type II) muscle fibres. ACTN3 gene variant NM_001104.4:c.1729C>T (p.R577X, rs1815739) in a homozygous state reduces strength, muscle mass, and fast-twitch fibre diameter and was asso-ciated with a higher risk of sports injuries and longer exer-cise recovery. We aimed to evaluate the association of the p.R577X with injuries and player position in Slovenian fema-le football players. The study group included 43 participants, with a median age of 16 (13-28) years, who had been acti-vely training football for at least 4 years. ACTN3 p.R577X genotyping was performed with PCR and DdeI restricti-on analysis on saliva DNA. p.R577X in the homozygous or heterozygous state was present in 58.1 % of the players, while 41.9 % had normal genotype. 53.7 % had a four ye-ars history of at least one sports injury. In our study, no sta-tistically significant association was found between ACTN3 p.R577X genotypes and the presence of injuries (p = 0.309), nor between the presence of injuries and player position (p = 0.830) or age dependant category team (p = 0.427). However, we confirmed the association between the presence of inju-ries and the frequencies of each allele (p = 0.037), with the X allele being associated with a higher incidence of injuries"},"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-H4I18EGD","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-H4I18EGD"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-H4I18EGD/6f2-b82c3e1ead-fadbd4b-117044995f1f-/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:dataProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-H4I18EGD/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-H4I18EGD"}}}}