34 KB161 KB30 KB199220252005Ciolan, MariaOlariu, LiviuSolovan, Caiusletnik:14številka:4str. 127-135ISSN:1318-4458COBISSID:20564953URN:URN:NBN:SI:doc-FLMM73H3enSlovene Welding SocietyActa dermatovenerologica Alpina, Pannonica et AdriaticadermatologijaDiagnosisdiagnostikaEpidermoliza bulozna, povezanaEpidermolysis Bullosa, JunctionalPathologyTherapyThe biomolecular and ultrastructural basis of epidermolysis bullosa|Transmission electron microscopy, immunoelectron microscopy, immunofluorescence and antigenic mapping have improved our understanding of the dermo-epidermal junction. We have reviewed some ultrastructural and biomolecular aspects related to the dermo-epidermal junction. In part, they are implicated in the pathogenesis of a group of hereditary disorders characterized by skin fragility, collectively known as epidermolysis bullosa (EB). These disorders could benefit in the near future from a gene therapy approach but at present genetic counseling, prenatal diagnosis and conservative treatment measures offer little real benefit to patientsTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaZdruženje slovenskih dermatovenerologov