32 KB198 KB32 KB200520252007Kos, JankoObermajer, NatašaVozelj, Suzanaštevilka:4letnik:586 stranistr. 133-138ISSN:0014-8229COBISSID:2230385URN:URN:NBN:SI:doc-C1NROSH7slSlovensko farmacevtsko društvoFarmacevtski vestnikkazalcilaboratorijska diagnostikaproteazerak (medicina)Proteaze in njihovi inhibitorji v telesnih tekočinah kot diagnostični in prognostični tumorski kazalci|In recent years the discovery of new cancer biomarkers has become an importantpart in cancer research. Biomarkers are useful for diagnosis, monitoring disease progression, and predicting disease recurrence and outcome and therapeutic treatment efficacy. Among various biomolecules involved in cancer development and progression, proteases and their inhibitors in tumors as well as in some body fluids may provide new diagnostic and prognostic information for cancer patients. The results of their clinical investigations in body fluids of human breast, ovarian, uterine cervix, uterus, bladder, lung, liver, head and neck, prostate and colorectal cancer show possible advantage over currently existing techniquesOdkrivanje novih tumorskih kazalcev je postalo pomemben del raziskav raka. Njihova uporabnost je v diagnozi, spremljanju napredovanja bolezni, pri napovedi ponovitve in izida bolezni ter spremljanju ueinkovitosti zdravljenja.Med mnogimi bioloskimi molekulami, ki so vpletene v procese razvoja in napredovanja raka, nam lahko prisotnost proteaz in njihovih inhibitorjev v tumorjih ali telesnih tekoeinah omogoei nove diagnostiene in prognostiene informacije za bolnike z rakom. Rezultati klinienih raziskav telesnih tekoein bolnikov z rakom dojke, jajenikov, maternienega vratu, maternice, mehurja, pljue, jeter, glave in vratu, prostate in erevesja kazejo na moene prednosti pred metodami,ki se trenutno uporabljajoTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko farmacevtsko društvo