59 KB696 KB27 KB199220252010Bunc, GorazdPopović, MaraSmrdel, UrošVelnar, Tomažštevilka:1letnik:446 stranistr. 13-18, IISSN:1318-2099COBISSID:3592255URN:URN:NBN:SI:doc-BW1JNRRSenAssociation of Radiology and OncologyRadiology and oncology (Ljubljana)DiagnosisDiagnostikaEpidemiologijaEpidemiologyEtiologijaEtiologyGenetic markersGenetski markerjikemoterapijamarkerjimožganiNeoplasmsNovotvorbeOligodendrogliaOligodendroglijaonkologijaprognozaTherapytumorZdravljenjeGenetic markers in oligodendroglial tumours|Background. Oliogodendrogliomas are brain tumours composed of the cells resembling oligodendrocytes. They represent the third most common glial tumour, comprising 2.5% of all primary brain tumours and 5-20% of all gliomas. Conclusions. Oligodendroglial tumours with 1p and 19q loss demonstrate a better overall prognosis due to more indolent clinical behaviour and higher sensitivity to treatment. Additionally, 1p and 19q loss is a marker of clinical utility, helping to assess tumour sensitivity to chemotherapy and harbouring the potential for improving the diagnosis and survival of oligodendroglioma patients as well as future clinical practiceTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaDruštvo radiologije in onkologije