{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-BC65X0OW/b456008a-cf11-4b00-a4a4-0e33f50cd287/PDF","dcterms:extent":"242 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-BC65X0OW/255908b5-37cd-4eb7-8474-3bf1a02ebad8/TEXT","dcterms:extent":"33 KB"}],"edm:TimeSpan":{"@rdf:about":"2010-2025","edm:begin":{"@xml:lang":"en","#text":"2010"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-BC65X0OW","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:spr-UQS2GZJE"},{"@xml:lang":"sl","#text":"Slovenska pediatrija"}],"dcterms:issued":"2024","dc:creator":"Paro Panjan, Darja","dc:format":[{"@xml:lang":"sl","#text":"številka:3"},{"@xml:lang":"sl","#text":"letnik:31"},{"@xml:lang":"sl","#text":"str. 104-109"}],"dc:identifier":["DOI:10.38031/slovpediatr-2024-3-01","ISSN:1318-4423","COBISSID:213964547","URN:URN:NBN:SI:doc-BC65X0OW"],"dc:language":"sl","dc:publisher":[{"@xml:lang":"sl","#text":"Združenje pediatrov Slovenije"},{"@xml:lang":"sl","#text":"Združenje specialistov šolske in visokošolske medicine Slovenije"}],"dc:subject":[{"@xml:lang":"sl","#text":"encefalopatija"},{"@xml:lang":"sl","#text":"možgani"},{"@xml:lang":"sl","#text":"neonatalne konvulzije"},{"@xml:lang":"sl","#text":"nevroprotekcija"},{"@xml:lang":"sl","#text":"novorojenček"},{"@xml:lang":"sl","#text":"poškodba"}],"dcterms:temporal":{"@rdf:resource":"2010-2025"},"dc:title":{"@xml:lang":"sl","#text":"Neonatalna nevrologija| preteklost, sedanjost in prihodnost| Neonatal neurology, past, present and future|"},"dc:description":[{"@xml:lang":"sl","#text":"The beginning of neonatal neurology dates back to the fifties of the last century, when the criterion of normality or optimal functioning of the central nervous system on the one hand and abnormalities on the other were set. This was followed by the development of imaging methods, which made it possible to recognize bleeding in the cerebral ventricles and damage to the white matter of the brain - periventricular cystic leukomalacia; later on magnetic resonance imaging significantly contributed to the understanding of the complexity of brain injury in premature and term infants. The development of electroencephalography has provided insight into the brain maturation and has made a key contribution to the understanding of the nature of neonatal seizures. Advances in basic science have contributed to the understanding of the mechanisms of brain damage at the cellular level and to the initiation of neuroprotection. The current era of neonatal neurology has focused on the concept of neonatal injury leading to impaired brain development - secondary dysmaturation and on new options of neuroprotection. In the future, we primarily expect an improvement in the level of neuroprotection, additional development of genetic diagnostics and treatment, and thus the development of the personalized medicine"},{"@xml:lang":"sl","#text":"Začetek neonatalne nevrologije sega v 50. leta prejšnjega stoletja, ko se je z vrednotenjem nevroloških znakov izoblikovalo merilo normalnosti oz. optimalnosti delovanja osrednjega živčevja (OŽ) na eni strani in nenormalnosti na drugi. Sledil je razvoj slikovnih metod, ko je z ultrazvočno preiskavo postalo možno prepoznati krvavitev v možganske prekate in poškodbo bele možganovine – obprekatno cistično levkomalacijo; v nadaljevanju je magnetnoresonančno slikanje pomembno prispevalo k razumevanju kompleksnosti možganske poškodbe nedonošenega in donošenega novorojenčka. Razvoj elektroencefalografije je omogočil vpogled v zorenje OŽ ter odločilno prispeval k razumevanju narave neonatalnih konvulzij. Napredek bazične znanosti je pri-speval k razumevanju mehanizmov možganske okvare na celični ravni ter začetku nevroprotekcije. V današnjem času sta pri možganski poškodbi nedonošenčka v ospredju raziskovanje dismaturacije – procesa sekundarne okvare, ki jo sproži prezgodnje rojstvo ter iskanje dodatnih možnosti za nevro protekcijo. V prihodnosti v prvi vrsti pričakujemo izboljšanje ravni nevroprotekcije, dodaten razvoj genetskih preiskav in zdravljenja ter s tem razvoj t. i. personalizirane medicine"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-BC65X0OW","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-BC65X0OW"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-BC65X0OW/b456008a-cf11-4b00-a4a4-0e33f50cd287/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by-nc/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Društvo za pomoč otrokom s presnovnimi motnjami"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-BC65X0OW/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-BC65X0OW"}}}}