19 KB272 KB16 KB200820252011Arko, DarjaDovnik, AndražFokter Dovnik, NinaTakač, Iztokštevilka:2letnik:4str. 45-50ISSN:1855-5640COBISSID:4160575URN:URN:NBN:SI:doc-AWHPVE0RenMedicinska fakultetaActa medico-biotechnicaCervical Intraepithelial NeoplasiaCervikalna intraepitelijska neoplazijaGinekološki kirurški postopkiGynecologic Surgical ProceduresPooperativna krvavitevPostoperative HemorrhageReproductive Tract InfectionsReproduktivni trakt, okužbeA prospective study of the correlation between infection of the uterine cervix and secondary bleeding after large loop excision of the transformation zone (LLETZ)| Prospektivna raziskava povezave med okužbo materničnega vratu in sekundarno krvavitvijo po eksciziji transformacijske cone z električno zanko (LLETZ)|Purpose: A prospective study was undertaken to evaluate the role of genital pathogens in postoperative bleeding necessitating secondary intervention after large loop excision of the transformation zone (LLETZ) of the uterine cervix. Methods: A total of 1419 patients with cervical intraepithelial neoplasia (CIN) who underwent LLETZ were included in the study. To determine the presence of genital pathogens, cervical swabs were collected before the procedure. Postoperatively, patients were followed up for bleeding necessitating secondary interventions. Results: Among 1419 patients, genital pathogens were present in 714 (50.3%) cases and absent in 705 (49.7%) cases. The most frequently isolated groups of microorganisms were group-B ß-haemolytic streptococci, alpha-haemolytic streptococci, Enterococcus sp. and coliforms. Secondary procedures due to severe bleeding were required in 48 (6.8 %) patients without and in 63 (8.8%) patients with genital pathogens, but this difference was not significant (chi-square test = 1.72; P>0.05). Conclusion: These data suggest that genital pathogens are very common in patients with CIN and are not an important cause of postoperative bleeding necessitating secondary intervention after LLETZNamen: Namen prospektivne raziskave je bil ugotoviti, ali okužba spolnega trakta s patogenimi mikroorganizmi vpliva na pojavljanje hude pooperativne krvavitve, ki zahteva sekundarni poseg po eksciziji transformacijske cone z električno zanko (LLETZ). Metode: V raziskavo je bilo vključenih 1.419 bolnic s cervikalno intraepitelijsko neoplazijo (CIN), pri katerih smo opravili LLETZ. Pred posegom smo bolnicam odvzeli bris materničnega vratu na patogene mikroorganizme. Po posegu smo pri bolnicah spremljali pojav hudih pooperativnih krvavitev, ki so zahtevale sekundarni poseg. Rezultati: Patogeni mikroorganizmi so bili prisotni pri 714 (50,3 %) bolnicah in odsotni pri 705 (49,7 %) bolnicah. Najpogosteje izolirani patogeni mikroorganizmi so bili ß-hemolitični streptokoki skupine B, alfa-hemolitični streptokoki, enterokoki in koliformne bakterije. Revizija zaradi hude pooperativne krvavitve je bila potrebna pri 48 (6,8 %) bolnicah brez patogenih mikroorganizmov in 63 (8,8 %) bolnicah s pozitivnimi brisi na patogene mikroorganizme. Razlika ni bila statistično značilna (hi-kvadrat = 1,72; P > 0,05). Zaključek: Bolnice s CIN imajo zelo pogosto prisotno okužbo materničnega vratu s patogenimi mikroorganizmi. Ta okužba ni pomembno vzročno povezana s pojavom hude pooperativne krvavitve, ki zahteva sekundarni poseg po LLETZTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaUniverza v Mariboru, Medicinska fakulteta