16175 KB16 KB199220252022Fister, MišaGlinšek Biškup, UrškaLuzar, BoštjanLuzar, BoštjanMikuž, UršaNoč, MarkoŠoba, BarbaraŠterbenc, Anjaletnik:31številka:iss. 2str. 79-81DOI:10.15570/actaapa.2022.11COBISSID_HOST:114008579ISSN:1318-4458URN:URN:NBN:SI:doc-AL4X9Z4QenSlovene Welding SocietyActa dermatovenerologica Alpina, Pannonica et Adriaticahyperinfection syndromesindrom hiperinfekcijeStrongyloides stercoralistransplanttransplantacijaDiagnostic challenge of Strongyloides stercoralis hyperinfection syndrome| a case report|Strongyloides stercoralis causes chronic, mostly asymptomatic infections but hyperinfection syndrome may occur in immunosup- pressed patients, especially in those receiving corticosteroids. We report a case of S. stercoralis hyperinfection syndrome in a solid organ transplant recipient that occurred approximately 2.5 months after heart transplantation. The patient presented to the inten- sive care unit with acute respiratory distress, bacteremia, and petechial rash on abdomen and toe. Microbiology testing of respira- tory samples excluded infection with Pneumocystis jirovecii, respiratory viruses, pathogenic bacteria and fungi. No eosinophilia was found. Histopathological examination of the skin biopsy of the petechial rash provided the first indication of the diagnosis, revealing the presence of isolated filariform S. stercoralis larvae in the dermis. Subsequent microbiology testing confirmed the diagnosis. This case highlights the role of histopathological examination of a skin rash in diagnosing patients with atypical clinical presentation of Strongyloides hyperinfection syndromeTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaZdruženje slovenskih dermatovenerologov