117 KB241 KB73 KB199220252008Kamenšek, UrškaSerša, Gregorštevilka:3letnik:42str. 115-135ISSN:1318-2099COBISSID:655483URN:URN:NBN:SI:doc-A62JN26ZenAssociation of Radiology and OncologyRadiology and oncology (Ljubljana)Gene therapygenska terapijaonkologijaradioterapijaRadiotherapyTargeted gene therapy in radiotherapy|The dramatic pace in development of gene therapy over the past decades has made it a realistic alternative for the treatment of cancer. Radiotherapy, on the other hand, is one of the most commonly used and well established cancer treatment modalities. The latest improvements in the physical targeting ability of radiotherapy and understanding of the molecular mechanism involved in the cellular response to ionizing radiation have presented an opportunity to combine radiotherapy with gene therapy. This review article will focus on gene therapy strategies that can be used to enhance the effectiveness of radiotherapy, with an emphasis on transcriptional targeting approachesTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaDruštvo radiologije in onkologije