{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-8DE3ACHU/9466005f-7da6-4c97-b5cf-8d2fe28e1195/PDF","dcterms:extent":"2039 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-8DE3ACHU/171771c2-5ca8-4ded-9662-55d0007b241e/TEXT","dcterms:extent":"40 KB"}],"edm:TimeSpan":{"@rdf:about":"2005-2025","edm:begin":{"@xml:lang":"en","#text":"2005"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-8DE3ACHU","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:spr-8ER5ZBJN"},{"@xml:lang":"sl","#text":"Farmacevtski vestnik"}],"dcterms:issued":"2020","dc:creator":["Gašperlin, Mirjana","Zupančič, Špela"],"dc:format":[{"@xml:lang":"sl","#text":"številka:3"},{"@xml:lang":"sl","#text":"letnik:71"},{"@xml:lang":"sl","#text":"str. 205-214"}],"dc:identifier":["ISSN:0014-8229","COBISSID_HOST:31798787","URN:URN:NBN:SI:doc-8DE3ACHU"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko farmacevtsko društvo"},"dc:subject":[{"@xml:lang":"sl","#text":"Dostavni sistem"},{"@xml:lang":"sl","#text":"Kozmetični izdelki"},{"@xml:lang":"sl","#text":"lipidni dostavni sistemi"},{"@xml:lang":"sl","#text":"Minerali"},{"@xml:lang":"sl","#text":"nanodostavni sistemi"},{"@xml:lang":"sl","#text":"Prehranska dopolnila"},{"@xml:lang":"sl","#text":"Vitamini"},{"@xml:lang":"sl","#text":"Zdravila"}],"dcterms:temporal":{"@rdf:resource":"2005-2025"},"dc:title":{"@xml:lang":"sl","#text":"Ali lahko z dostavnimi sistemi izboljšamo učinkovitost vitaminov in mineralov?| Can the delivery systems improve the efficiency of vitamins and minerals?|"},"dc:description":[{"@xml:lang":"sl","#text":"Vitamins and minerals are essential for the functioning of human body and the prevention of diseases. It is desirable to consume an adequate amount with balanced and varied food. However, when this is not possible, they are available as medicinal products, nutritional supplements and cosmetics. Conventional dosage forms, such as tablets, capsules, effervescent tablets and powders for oral use are currently still predominant on the market. Due to the challenging stability, low solubility and bioavailability there is a need to improve the efficacy of vitamins and minerals. One possible way is development of novel advanced delivery systems, the most important among which are liposomes, micro- and nanoemulsions, self(micro)emulsifying systems, solid lipid nanoparticles and nanostructured lipid nanocarriers"},{"@xml:lang":"sl","#text":"Vitamini in minerali so nujno potrebni za delovanje človeškega telesa in preprečevanje bolezni. Zaželeno je, da potrebno količino zaužijemo z uravnoteženo in raznovrstno hrano. V primerih, ko pa to ni mogoče, so na voljo v obliki zdravil, prehranskih dopolnil in kozmetičnih izdelkov. Trenutno na tržišču še vedno prevladujejo klasične farmacevtske oblike, kot so tablete, kapsule, šumeče tablete in praški za peroralno uporabo. Zaradi problematične stabilnosti, slabše topnosti in biološke uporabnosti vitaminov in mineralov pa se razvijajo napredni dostavni sistemi, med katerimi so najpomembnejši liposomi, mikro- in nanoemulzije, samo(mikro)emulgirajoči sistemi, trdni in nanostrukturirani lipidni nanodelci, ki predstavljajo enega izmed načinov za izboljšanje učinkovitosti vitaminov in mineralov"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-8DE3ACHU","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-8DE3ACHU"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-8DE3ACHU/9466005f-7da6-4c97-b5cf-8d2fe28e1195/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko farmacevtsko društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-8DE3ACHU/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-8DE3ACHU"}}}}